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Biomedical subjects

E Brander

Publications and source records attributed to E Brander.

35 records · Page 2Linked to original sources

An epidemic of mild pneumonia due to an unusual strain of Chlamydia psittaci.

An epidemic of mild pneumonia was discovered during a chest radiographic survey of adolescents and young adults in two communities 110 kilometers apart in northern Finland. Antibodies to chlamydial antigens were found in 32 of 34 persons with pneumonitis. Microimmunofluorescence antibody tests suggest that the etiologic agent is closely related or identical to TW-183, an unusual strain of Chlamydia psittaci isolated from the eye of a child in Taiwan. The point prevalence of pneumonitis with antibody to TW-183 in school children at the time of the survey was high-15 and 19 patients per 1,000 students in the two communities. There was no evidence of avian transmission in the epidemic.

Adolescent↗

Tuberculosis of the cervical lymph nodes : a clinical, pathological and bacteriological study.

Biopsies taken from the lymph nodes of 59 consecutive patients with cervical lymph node tuberculosis were examined bacteriologically and histologically. The series consisted of 18 men (mean age 40 years) and 41 women (mean age 46 years). Mycobacteria were isolated from 41 specimens (69 per cent), M. tuberculosis from 40 patients and a mycobacterium of the M. avium-M. intracellulare complex from one. All the M. tuberculosis strains were sensitive to streptomycin, isoniazid and PAS. No mycobacteria were isolated from the biopsy specimens of the 10 patients who had received anti-tuberculosis drug previously. Mycobacteria were isolated equally often from caseating and non-caseating lymph nodes. In 10 specimens acid-fast bacilli could be demonstrated by staining, but attempts at isolation were unsuccessful. Nine of these 10 patients had been treated with anti-tuberculosis drugs previously. Histological examination of the specimen from which a growth of 'atypical' mycobacteria had been obtained failed to show any distinctive features. The results of treatment are given over a follow-up period of 2 years. Primary chemotherapy was not entirely successful. Of 52 patients treated in this way only 38 responded well. By contrast 19 patients were treated by a combination of chemotherapy and surgery and the outcome was satisfactory in all but one.

Adult↗