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Biomedical subjects

E Bodner

Publications and source records attributed to E Bodner.

At least 73 records · Page 4Linked to original sources
PubMed1989

Gastric stump cancer: etiopathological and clinical aspects.

Between 1959 and 1987, at the Innsbruck University Hospital, 359 cases of carcinoma were diagnosed in the gastric remnant. While until 1975 in 203 patients suffering from stump carcinoma the tumor stages T3 and T4 were significantly prevalent, a strong tendency towards the less advanced tumor stages T1 and T2 was observed in the last decade. Among 94 patients operated on since 1981 the tumor was located at the anastomosis in all but 5 cases, suggesting a strong connection between previous resection and stump carcinoma. In accordance with Lauren's classification no difference was found in the incidence of intestinal and diffuse lesions in 94 cases with stump carcinoma--in contrast to 69 cases of patients with a non-resected stomach. An analysis of the occurrence of acidity, atrophic gastritis and bacterial invasion in 70 patients with previous Billroth II resection and 30 patients with Billroth I resection, revealed no difference between the two types of resection. Gastric remnant carcinoma does not occur exclusively in the Bilroth II remnant, but, increasingly, following Billroth I operations. The finding of a statistically highly significant increase at the 5% level using standard chi 2-technique for a 2 x 5 table in stump carcinomas following Billroth I resections supports the thesis that there is no difference in the etiopathology of carcinogenesis in the Billroth I as compared with the Billroth II remnant.

Aged↗
PubMed1988

[Palliative surgery in colorectal cancer].

Only about 20% of all operative measures in colorectal cancer patients are performed in palliative intention. Surgical strategies, however, need to be selected in correspondence to the symptomatological end of the operation. If possible, a simple but complete removal of the tumor should be attempted.

Colonic Diseases↗
PubMed1988

Early cancer of the gastric remnant.

Early carcinoma of the gastric remnant was diagnosed in 19 patients between January 1976 and January 1986. In all patients early cancer was suspected at endoscopy and confirmed by biopsy and histology. The main reason for endoscopic examination was diffuse epigastric pain suggestive of stump gastritis. The surgical procedure was stump gastrectomy. Two of the 19 patients were not operated on because of advanced age. In contrast with the poor prognosis of patients with cancers of the gastric remnant of tumour stages T2 to T4 according to the TNM-classification regardless of their NM-stage, patients with tumour stage T1N0 and T1N1 have a good prognosis.

Adult↗
PubMed1988

[Achievements of tumor surgery in tumors of the pancreas].

In a retrospective analysis of 274 cases of ductal pancreatic cancer (uniform resection technique, no total pancreatectomy de principe) the resection rate was 28.1%, the death rate following duodenopancreatectomy 5.8%, cumulative 5-year-survival rate 11% in resected patients compared to 2.6% in all patients. Although discouraging, these results are still superior to non-surgical treatment. Three of four long-term survivors (greater than 5a) died from recurrent cancer. The question arises whether pancreatic cancer is surgically curable at all?

Aged↗
PubMed1987

[Intraoperative radiotherapy of malignant pancreatic tumors--initial results].

Thirteen patients suffering from adenocarcinomas of the pancreas were submitted to an intraoperative fast electron "boost" therapy with or without percutaneous photon irradiation. A duodeno-cephalo-pancreatectomy with subsequent irradiation of the tumor bed could be performed in three patients. Ten patients were inoperable because of advanced tumors and formation of metastases. The average survival is 6.5 months, at present six patients are alive without major troubles. An analgetic effect was obtained in ten patients. The first results are encouraging with respect to local control, the little acute and chronic morbidity, and palliation achieved in advanced stages.

Adenocarcinoma↗
PubMed1986

[Intraoperative radiation treatment of carcinoma of the pancreas. Initial clinical results].

Intraoperative radiotherapy (IORT) was administered to 13 patients with carcinoma of the pancreas, using high-velocity electrons of a LINAC accelerator in a single dose of maximally 25 Gy applied directly to the tumour or tumour bed with the abdomen open. There were no disorders of wound healing or other serious early complications which could be ascribed to the radiation. Stomach and intestines were excluded from the radiation field to avoid late radiation damage, such as stenoses or ulcers. The method is particularly indicated for locally non-resectable, non-metastasized pancreatic carcinoma, possibly also as tumour-bed radiation during radical surgery. Patients with distant metastases were not given radiation. First results point to IORT providing lasting improvement of pancreatic pain. It is too early to know whether survival time is favourable influenced.

Aged↗
PubMed1986

Aneurysm of the proper hepatic artery as a rare source of upper gastrointestinal bleeding.

The rare case of the penetration of a partially thrombosed aneurysm into the duodenal bulb causing acute upper gastrointestinal bleeding is described. Besides angiography and CT, ultrasound is the method of choice for early detection. In any case of upper gastrointestinal bleeding of unclear origin the existence of an arteriointestinal fistula should be included in the differential diagnosis.

Aneurysm↗
PubMed1985

Clinically controlled comparative study of suprofen, pentazocine, and placebo. Experience with intramuscular single doses.

Analgesic effect and tolerability of alpha-methyl-4-(2-thienylcarbonyl)-phenylacetic acid (suprofen, Suprol) 200 mg were compared with pentazocine 30 mg and placebo in 88 patients in moderate to severe postoperative pain. The trial was designed as a randomized single-blind study; the test drugs were in single doses (1 ml ampuls) administered by deep intragluteal injection in the upper outer quadrant. The test population was homogeneous as to anamnestic data; the initial intensity of pain was comparable in all three groups. Statistical analysis of the obtained data revealed that at the rating times 30 min to 3 h suprofen was statistically significantly superior to placebo, while after 2 h it was significantly superior to pentazocine. The investigator's final global appreciation of effectiveness states moderate to good effect in 86% of the patients on suprofen, 76% of those on pentazocine, and 63% of the subjects on placebo. Significant difference existed only between suprofen and placebo. Systemic tolerability was considered good to very good in 97% of the subjects in all three treatment groups, whereas local tolerability was considered poor in 2 patients (6.9%) in the group on suprofen. There were no significant differences between the medications. Two subjects each on suprofen and pentazocine and 1 patient on placebo experienced side effects.

Adult↗
PubMed1982

[Rationalisation of surgical diagnosis by means of real-time sonography].

A report is given of the results obtained on implementing sonography routinely in the diagnosis of general surgical conditions. Fields in which this procedure has proved of particular value are acute surgical emergencies, polytrauma, biliary surgery, post-operative complications, septic processes, palpable abdominal masses and the investigation and follow up of patients with tumours. Ultrasound-directed fine-needle puncture plays an important role within this last-mentioned group of indications. In order to make optimum use of sonography in interpreting specifically surgical problems, this readily-available bedside examination is performed by the experienced surgeon himself. Further diagnostic tactics and their consequences are discussed.

Biliary Tract Diseases↗