Biomedical subjects
Publications and source records attributed to E Bodard-Rickelman.
We report a case of cryptococcal chorioretinitis discovered at ophthalmological examination of a 68-year-old woman with acquired immune deficiency syndrome. This localization revealed cryptococcal septicemia, without involvement of the central nervous system unlike most cases reported. Therapy with fluconazole (400 mg per day) led to gradual regression of the chorioretinal lesion.
We report two cases of frontal and ethmoidal mucocele revealed by severe ophtalmologic complications and present the clinical data and computed tomography and magnetic resonance imaging results together with the treatment. The surgical approach and technique are discussed. Recovery of ophtalmologic deficiency was excellent.
The description of a case of orbitary thrombosis leads to discuss the origin of orbitary thrombosis, and their links with Tolosa Hunt syndrome. The case which is studied is associated with beginning rheumatoid polyarthritis.
Acute renal failure due to tubulo-interstitial nephritis developed in a 12 year old boy. It was accompanied by an inflammatory syndrome consisting of a markedly increased erythrocyte sedimentation rate and high levels of C. reactive protein and fibrin. The association of these anomalies with an uveitis are typical of the Tinu syndrome (tubulo-interstitial nephritis uveitis) first described by Dobrin and al. in 1975. The interest of this case lies in the observation of focal chorioretinitis, as yet never described. The possibility of toxoplasmosis is discussed; it could be a direct etiologic factor or could represent a concurrent phenomenon. However no evidence of toxoplasmic infection could be demonstrated in this case, nor in any case previously reported. Light microscopic examination of a renal biopsy reveals diffuse monocellular interstitial infiltration and epithelioid granulomas. In some cases, non-specific bone marrow and lymph node granulomas have been found. In the Tinu syndrome, the nephropathy is completely reversible, either spontaneously or following steroid treatment; this contrasts with the tendency towards relapse of the uveitis. The possible pathogenesis and the relationship with other idiopathic acute nephritis and uveitis are discussed. As in some previous publications, the presence of circulating immune complexes in our patient would suggest the involvement of the immune system. Temporary depression of cellular immunity was also observed in some cases. But the etiology and the pathogenesis of this syndrome are still unknown.
The authors remind some essential notions on Hashimoto's thyroiditis, and sum up the recent data on the physiopathology of the main auto-immune thyroid disturbances. One case of Hashimoto's thyroiditis diagnosed through out atypical ophthalmological symptoms, leads the authors to formulate different hypothesis integrating all the elements of this case in a single nosographical system, following a review of the literature on thyroid ophthalmopathy.
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The authors present seven cases of vitelliform macular dystrophy in two families. The cases comparison leads to oppose two different types: the classical type and the adult type with similar ophthalmoscopical and angiographical aspects but different genetical expressivity, evolution, and above all, different electrophysiological answer.
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