Search PubMed⌕ Search

Biomedical subjects

E Bernacki

Publications and source records attributed to E Bernacki.

49 records · Page 3Linked to original sources
PubMedDate not supplied

Hepatic focal nodular hyperplasia: CT and sonographic spectrum.

Fifteen patients with pathologically proven focal nodular hyperplasia (FNH) of the liver had abdominal computed tomography (CT) (15) and ultrasound (11). In seven patients, the lesions were incidentally found during gallbladder or renal examination, whereas the other eight had a primary neoplasm and the liver was studied for possible metastasis. In 11 unenhanced CT scans, the ratio of isodense to hypodense lesions was 8 to 3. In 15 contrast-enhanced CT scans, seven were isodense, six were hypodense, and in two, the lesion enhanced (hyperdense). In seven patients a hypodense lesion on unenhanced CT became isodense with contrast injection. Delayed images in three showed the lesions appearing as hypodense in two and displaying a rim of enhancement in one. In one case, unenhanced CT was normal and only enhanced CT showed an area of homogeneous increased density. Ultrasound was done in 11 patients, the lesion was hypoechoic to the liver in five, echogenic in four, and isoechoic in two. Findings of central scar were seen on CT and ultrasound in three cases. Pathologic diagnosis was available in all cases, seven by needle aspiration and eight by surgical resection. In our experience, FNH has many CT and sonographic features that can mimic hemangioma or metastasis. While the presence of a central scar increases the specificity, in a cancer patient, the findings should be interpreted with caution and needle aspiration should be obtained.

Adult↗
PubMedDate not supplied

Studies on the exocrine function of healthy human pancreas: pancreatic juice and its certain components.

The exocrine function of healthy pancreas was studied continuously during 9 days in a 28-year-old man. Pancreatic juice was collected by means of a drain passed into Wirsung's duct. The 24-hour volume of the juice was 1118 +/- 117 ml. In daytime the mean rate of juice secretion was 56 ml/hour and in the night it decreased to 20 ml/hour. Amylase and lipase activity in the pancreatic juice was very high and significantly higher in nocturnal secretion. Administration of 2% HCL or secretin (1.5 mu/kg) increased the volume of juice by 30 ml in the following hour without changes in the activities of amylase and lipase. Atropine ephedrine and pancreatin reduced the juice volume by 20-40 ml but the enzymatic acitivity decreased only after atropine. The rise in the juice volume was associated with an increase in its HCO3 concentration and a fall in CL- concentration. The levels of Ca++, K+ and Na+ as well as protein were also determined and it was found that protein concentration in the juice ranges from 0.1 to 4.1 g/100 ml.

Adult↗