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Biomedical subjects

E Berger

Publications and source records attributed to E Berger.

At least 145 records · Page 8Linked to original sources
PubMed1981

[An unusual case of repeated self mutilation (author's transl)].

An unusual case is presented of repeated, life-threatening self mutilation, elicited by the topical application of sodium hydroxide, which necessitated several operations, including amputation of the left lower leg. Histological examination revealed colliquation necrosis and a striking eosinophilia. The latter feature, which was not reproducible in an animal experiment, may be related to a defect of leucocyte locomotion in the present case.

Adolescent↗
PubMed1981

Puerperal febrile complications and cervical flora following elective manual exploration of the uterus.

Two hundred patients who underwent vaginal delivery were randomly divided into two groups on arrival to the case room in labor. After delivery was completed the uteri of 100 patients were manually explored; the remainder of the patients served as a control group. Aerobic and anaerobic cultures of the endocervix were taken from 50 patients in each group, during labor and on the fourth postpartum day. There was no difference in the number of puerperal febrile complications between the groups. Endocervical cultures showed a marked increase in the incidence of Escherichia coli and anaerobic bacteria after delivery. This increase occurred in both groups in similar proportions and was not affected by manual exploration.

Bacterial Infections↗
PubMed1981

Some isometric embedding and rigidity results for Riemannian manifolds.

In this note, we announce some new results concerning rigidity and isometric embeddings of Riemannian manifolds. A special case of the main result states that a general M(n) [unk] R(n+r), r</=(n - 1)(n - 2)/2, is uniquely determined up to finitely many constants by its induced ds(2).

Journal Article↗
PubMed1980

[Neurological and psychiatric manifestations in Mycoplasma pneumoniae infections in childhood (author's transl)].

The questions of a causal connection between Mycoplasma pneumoniae infection and neurological psychiatric diseases is discussed on the basis of the case reports of two patients and a review of the literature. Since a causal connection can be assumed in the reported cases it is suggested that infection by Mycoplasma pneumoniae infections should be included in the differential diagnosis of aetiologically unclarified meningoencephalitis, polyradiculitis, and organically-based psychoses.

Adolescent↗
PubMed1980

Acetylcholinesterase induction by beta-ecdysone in Drosophila cell lines and their hybrids.

Drosophila S3 line cells maintain a high basal level of acetylcholinesterase (AChE) activity, which is lost and then reinduced following exposure to the steroid, beta-ecdysone. Electrophoretic studies indicate that the basal and reinduced AChE activities may be different isozymes. In contrast, MDR line cells have a low basal AChE activity which is induced to a modest level by hormone. In S3/MDR hybrids the high basal level phenotype is extinguished, and the hormone-induced AChE level is modest. MDER line cells, which continue to grow in the presence of beta-ecdysone and are therefore termed resistant, show a low basal AChE level that is not further elevated by hormone. This phenotype and response also occurred in beta-ecdysone-resistant S3/MDER hybrids.

Acetylcholinesterase↗
PubMed1980

Pattern of peptide synthesis in Drosophila cell lines and their hybrids.

Significant changes occurred in the rate of synthesis of several polypeptides in two different Drosophila cell lines following exposure to the steroid hormone, beta-ecdysone. For peptide 7/8, the synthetic rate increased by a factor of 10 in line S3 and by a factor of 1.3 in line MDR. In hormone-sensitive hybrids the rate increased by a factor of 3-4.5. For peptide 10 the synthetic rate decreased by a factor of 8 in line S3 but increased by a factor of 2 in line MDR. In hormone-sensitive hybrids the synthetic rate increased by a factor of 2-3. In hormone-insensitive cell lines no change in the rate of peptide synthesis occurred in the presence of hormone.

Animals↗
PubMed1980

[On the reliability of case history data on parturition (author's transl)].

Case history data on the course of parturition (recorded during the sixth week of life and the twelfth month of life) are compared with each other, as well as with the actual course of parturition, within the framework of a prospective study covering the first year of life. The information regarding auxiliary obstetrical measures, position anomalies, as well as deviations from the normal weight at birth, were associated with a probability of error of less than five per cent. All other data regarding umbilical cord complications, asphyxia, etc. were associated with various error probabilities up to 20 per cent. It is concluded from these results that data on the history of parturition merely have the character of good estimates on account of their poor validity and reliability. This must be taken into account both in the statistical processing of medical data and in the employment of case history data for the pathogenetic interpretation of an actual disease picture, especially minimal cerebral dysfunction in children (MCD).

Asphyxia Neonatorum↗
PubMed1980

Calcium-induced erythrocyte rigidity: the roles of cellular metabolism, hydration, and ionic balance.

Previous investigations have shown that incubation of human erythrocytes with the ionophore A23187 and calcium causes accumulation of the cation, losses in potassium, water, and cellular volume, hydrolysis of adenosine triphosphate (ATP), conversion of biconcave discocytes to echinocytes and spheroechinocytes, and marked increases in erythrocyte resistance to micropipette aspiration. Subsequent studies demonstrated that prevention of water and potassium loss blocked the influence of calcium loading on erythrocyte stiffness without affecting calcium uptake by the cells or hydrolysis of ATP. In the present study erythrocytes were exposed to conditions that permitted individual or coordinate manipulation of cellular ATP, water, potassium, and calcium in order to determine which factors developing as a result of calcium loading were responsible for the calcium-induced changes in erythrocyte viscoelastic properties. Results of the study demonstrate that volume loss, ATP hydrolysis, and potassium depletion do not individually or in combination cause increases in erythrocyte stiffness. However, all of these changes are essential and must develop in conjunction with calcium loading in order for erythrocytes to develop diminished deformability and elasticity.

Adenosine Triphosphate↗
PubMed1980

[Motor functions in developmental-neurological diagnosis. Longitudinal study of low-risk infants. I. Normalization tendency, reflexes].

In a prospective longitudinal study, we investigated 91 low-risk infants on five occasions up to the end of their first year of life. We see that also after low-risk delivery, only four infants showed optimal neurological functions but it was shown too, that borderline-symptoms of the neonatal period have a clear tendency to normalize. We have selected some reflex-mechanisms in infancy and presented their changes. In comparison with other reports, we found that important differences between the results are dependent on techniques of examination and evaluation. The changes in reflex-mechanisms provide an insufficient basis therefore for developmental diagnosis (see second part).

Child Development↗
PubMed1980

[Motor functions and their analysis in the developmental neurology. Part II: Spontaneous motility and straightening functions (author's transl)].

In a prospective longitudinal study, we investigated all low-risk infants on five occasions up to the end of their first year of life. In the second part of the report, we present the developmental changes of spontaneous motility and straightening functions. The consideration of behavioural state is important for the outcome of neurological testing. The changes of spontaneous motility (intensity, speed and quantity of motions, startles, tremor, prehension ...) are sufficient parameters for developmental diagnosis. Some functions (goal directed arm-motion, prehension...) are correlated to environmental influences. The usual practice of developmental diagnosis is insufficiently directed to developmental processes in the CNS.

Child Development↗
PubMed1979

A precursor of cytoplasmic actin in cultured Drosophila cells.

In continuous lines of cultured Drosophila cells two forms of cytoplasmic actin, designated II and III, are detected after a 25- to 120-min pulse label with [35S]methionine. However, only one of these, actin II, accumulates in the cell. With the use of a pulse-chase protocol and two-dimensional gel electrophoresis, it has been found that actin III is synthesized as a precursor of the more stable cytoplasmic actin II. The half-life of actin III was estimated to be approximately 50 min.

Actins↗
PubMed1979

Ten years of national health service in Canada.

Ten years ago the medical profession in Canada was conscripted into a compulsory national health insurance scheme without any prior consultation. Predictions that an open-ended, so-called "free" medical insurance scheme would lead to cost overruns and deterioration of medical services as well as inflationary trends have come true. Federal and provincial governments now attempt to contain costs by closing active treatment beds or filling them up with chronic patients and by attrition of existing facilities. Compulsory national health insurance has not led to lower morbidity nor greater longevity. It has only provoked an insatiable demand from the public for more "free" services, with the result that the system has become a quagmire of cost overruns and unfulfilled and unrealizable promises.

Canada↗