Search PubMed⌕ Search

Biomedical subjects

E Barreto

Publications and source records attributed to E Barreto.

8 recordsLinked to original sources
PubMed1987

Pleural biopsy with Cope and Abrams needles.

The object of this study was to compare the diagnostic yield of Abrams and Cope needles. Pleural biopsies were performed in 24 patients with both needles. In two patients, the procedure was repeated within a few days. All patients had pleural effusion. The biopsies were performed at the same time; the biopsy sites were no more than 5 cm distant from each other. Diagnoses were exclusively pathologic. There was no difference between the needles in relation to diagnosis; greater size of the fragment, mesothelial cells, and fibrin were most frequently obtained by Abrams needle, while muscle was better obtained with the Cope needle. The biopsies with both needles were very similar regarding chronic inflammation, granuloma, caseous necrosis, neoplastic tissue, granulation, neutrophils, hemorrhage, vessels, nerves, adipose tissue and epidermis. The advantages of more pleural tissue obtained with the Abrams needle was not translated into better diagnostic yield in the present series.

Biopsy↗
PubMed1985

Cell mediated immunity in American cutaneous and mucosal leishmaniasis.

Cellular immune responses were studied in 35 Brazilian patients with either active cutaneous leishmaniasis (CL), active mucosal leishmaniasis (ML), or healed cutaneous leishmaniasis. The mean age and duration of illness in the two groups were as follows: 14 CL patients, age 28 +/- 13 yr, disease 5 +/- mo; and 16 ML patients, age 34 +/- 15 yr, disease 86 +/- 117 mo. Patients with CL and ML responded well to leishmania antigen in blastogenesis assays. However, the response of ML patients was over three times greater than the response of CL patients. There was a significant correlation between the magnitude of the lymphoproliferative response and the duration of disease activity. There were no significant differences between CL and ML patients in terms of the following parameters: lymphoproliferative responsiveness to mitogens (phytohemagglutinin, concanavalin A, and pokeweed mitogen) and peripheral blood lymphocyte subpopulations (T and B cells, oKT8+ and OKT4+ cells, OKT4:OKT8 ratio). Peripheral blood mononuclear cells from ML patients also generated interferon-gamma containing lymphokine in response to stimulation with leishmania antigen. This lymphokine was capable of inducing macrophages from ML patients to inhibit the intracellular multiplication of leishmania in vitro. These studies have determined that the parameters of lymphocyte and macrophage functions evaluated in ML and CL patients are comparable, except for an enhanced lymphoproliferative response, with leishmania antigen in ML patients. This later finding may be a function of the long duration of active disease in this population and unrelated to the pathogenesis of their mucosal lesions.

Adolescent↗
PubMed1983

[Rhinoentomophthoramycoses. Report of 4 cases].

Four cases of rhynoentomophthoramycosis are reported from urban areas of the states of Bahia and Maranhão, Brazil. The lesions presented with infiltration, redness and heat of the skin of the nose and infraorbital areas and accompanying nasal stuffiness. In on case the infiltration also involved the lips and mandibular area causing severe facial deformity. Microscopically, granulomatous reactions with small abcesses, fibrosis and a dense infiltration of eosinophils were found. Hyphae were seen frequently, always associated with the Splendore phenomenon. Three cases were treated completely with iodine. The one case resistant to iodine was cured with prolonged administration of sulphona. In two cases, plastic surgery was performed for facial reconstruction and nasal-unblocking respectively. Including the cases presented here, only 8 cases of rhynoentomophthoramycosis have been reported in Brazil, but the authors believe that this pathology muta occur more frequently. The lack of knowledge of its clinico-pathological aspects may be responsible for the delay or lack of diagnosis of this entity which occurred in two of the cases reported here.

Adolescent↗
PubMedDate not supplied

Cytology by capillarity and anatomopathological diagnosis of solid breast tumors.

A study was conducted on material obtained by capillarity puncture (74 punctures) from 71 patients with breast tumors. The material was fixed in absolute alcohol and stained by the Papanicolaou method and the result was classified as insufficient material, or as negative, suspect or positive cytology. After tumor exeresis, the anatomopathological results of each patient were compared to the cytology data. A single false-positive case was obtained among 44 patients (97% specificity) and 9 false-negative cases were obtained among 16 patients (56% sensitivity).

Adult↗