Search PubMed⌕ Search

Biomedical subjects

E B Howard

Publications and source records attributed to E B Howard.

At least 37 records · Page 2Linked to original sources
PubMed1982

Canine bladder epithelial cells in culture: susceptibility to canine distemper and measles viruses.

A canine bladder epithelial cell strain was established in culture for the study of canine distemper virus. Epithelial cells were scraped off the bladder with a scalpel and were cultured in enriched Eagle's medium. Cells were enzymatically dispersed and passed over 46 population doublings which covered a period of more than 3 years. The cells were heteroploid when karyotyped at passage level 5 and 42. This cell strain permitted direct isolation of canine distemper virus and also showed susceptibility to laboratory strains of measles virus. Seemingly, establishment of cell strains from canine bladder epithelium can be accomplished without difficulty.

Animals↗
PubMed1981

Urinary tract infection after injection of pseudomonas into bladder.

Pseudomonas urinary tract infection was studied in female mice. The bladder was exposed by a lower midline incision and an overnight washed culture of Pseudomonas (0.05 ml.) was injected into the bladder. This resulted in infection of the kidneys in more than 50 per cent of mice at one week. At four hours, the microulceration of the bladder was observed with many Pseudomonas int the base of the ulcer. The presence of acute inflammation on the serosal surface of the bladder, the frequent death of the mice, the presence of cortical foci of polymorphonuclear leukocytes in the kidneys, and bacteremia suggested that bacteremia may play a significant role in the development of the renal infection in this model of urinary tract infection. Bacteria injected through the bladder wall of mice cannot be assumed to produce ascending infection of the kidney.

Animals↗
PubMed1981

Avian practice.

Explore the source record for details and available documents.

Animals↗
PubMed1980

Pseudomonas urinary tract infection in mice.

When Pseudomonas aeruginosa was injected through a catheter into the bladder. Hemorrhage, edema, and vessel engorgement were seen 1 h after challenge. At 3 hours we observed microulceration of the bladder, which rapidly healed and was rarely present after 24 h. Pseudomonas was cultured from 50% of the kidneys at 1 week, and the number of kidneys infected decreased over 4 weeks.

Animals↗
PubMed1980

Psittacine tuberculosis.

Two cases of tuberculosis in psittacine birds were reported and the literature reviewed. One case was in a parakeet and this species was reported to be resistant to mycobacterial infection. No other case of parakeet tuberculosis was found in the literature. The other case was in a parrot. Historically, tuberculosis in parrots was common in European aviary collections, but case reports in the United States were few. The disease in parrots is of zoonotic interest, as they are unique among birds in being susceptible to mammalian strains of mycobacteria. The tuberculomatous aspect of the intestinal lesion in the parrot case described was unusual.

Animals↗
PubMed1979

Acute viral hepatitis in California sea lions.

Acute viral hepatitis was diagnosed in five California sea lions (Zalophus californianus) stranded along the Los Angeles coast. Light microscopy revealed large nuclear inclusion bodies in hepatocytes. Electron microscopy provided evidence that these inclusion bodies were composed of adenovirus-like virions. Attempts to grow the virus in cell culture systems were unsuccessful.

Adenoviridae↗