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Biomedical subjects

E B Gordon

Publications and source records attributed to E B Gordon.

7 recordsLinked to original sources

Transsexual healing: medicaid funding of sex reassignment surgery.

Federal requirements for state Medicaid programs are surveyed, and case law regarding Medicaid funding of sex reassignment surgery is reviewed. States have attempted to exclude sex reassignment surgery (SRS) from Medicaid coverage on various bases, concluding, for example, that the procedure constituted "cosmetic surgery." Judicial scrutiny of such exclusions has usually resulted in the state action being found violative of the federal Medicaid statute and accompanying regulations. In those cases upholding the state exclusion, the primary judicial obstacle to funding has been a determination that SRS is "not medically necessary" or is "experimental." The author explores the recent scientific literature concerning long-term outcomes following SRS and concludes that the procedure, for purposes of Medicaid funding, is neither "unnecessary" nor "experimental," and that the categorical exclusion of SRS from Medicaid coverage is therefore inappropriate. The author recommends case-specific determinations of eligibility for Medicaid funding, utilizing the standards of care promulgated by The Harry Benjamin International Gender Dysphoria Association.

Attitude to Health

Quantitative evaluation of chlortoluran-induced splenic hemosiderosis by means of an image analyzer.

This study investigated a technique for the quantification of hemosiderin layed down in the spleen. The model used was the rat to which the urea-based herbicide chlortoluran was fed for 90 days. There was good correlation between hematological, biochemical, histological and image analytical techniques when splenic hemosiderosis was of a moderate to severe degree. Where hemosiderosis was of a slight nature, only the technique of image analysis was able to detect the on-going changes.

Animals

Oxypertine in combination with imipramine: a controlled trial.

A method for the controlled assessment of two agents for possible interaction in the treatment of endogenous depression is described. This consisted of dose-ranging the supplementary agent (oxypertine 30 mg and 60 mg daily or matching placebo) during Week 2 to Week 6 having established all patients on a therapeutic dose of imipramine during Week 1. The reported enhancement of imipramine by oxypertine was not confirmed.

Adult

Family studies on the simian-type blood groups of chimpanzees.

Family studies were carried out the investigate the genetics of the chimpanzee simian type blood group systems V-A-B-D and C-E-F. In addition to providing new data, the studies confirm the validity of earlier results obtained by population genetics methodology for deducing genetic mechanisms in primate animals where family material cannot be obtained.

ABO Blood-Group System

Blood groups of pygmy chimpanzees (Pan paniscus): human-type and simian-type.

Blood grouping of nine pygmy chimpanzees revealed them to be human-type group A1, M,Rho, and simian-type V.D, CCef, g, H, I, K, L. Only group Nc was polymorphic. Pan paniscus red cells can be easily distinguished from those of Pan troglodytes by the serological characteristics of human-type blood groups A and M. Also, the distribution of the simian-type blood group systems V-A-B and C-E-F are strikingly different in the two species.

ABO Blood-Group System

Induction of gastrointestinal tumors in mice fed the fungicide folpet: possible mechanisms.

Dietary administration of the fungicide folpet, N-(trichloromethylthio) phthalimide, to B6C3F1 mice at dose levels of 1,000, 5,000 and 10,000 ppm induced a dose-related appearance of duodenal atypical hyperplasia, adenomas and adenocarcinomas. The appearance in some of these animals of gastric papillomas and gastric squamous cell carcinomas was correlated in many instances to the presence of duodenal obstructions. It is suggested that the gastric lesions appeared subsequent to, and as an indirect result of, these partial lumenal duodenal obstructions. We suggest that the presence of duodenal obstructions is consistent with the notion that reflux of folpet, bile acids and pancreatic enzymes into the stomach may have acted to irritate and consequently stimulate local neoplastic proliferation. In addition, the duodenal obstructions may have resulted in delayed emptying time of the stomach contents with consequential stagnation. This would cause high concentrations of folpet to act locally on the gastric mucosa.

Adenocarcinoma