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Biomedical subjects

E Aliot

Publications and source records attributed to E Aliot.

At least 145 records · Page 8Linked to original sources
PubMed1979

[Reentry tachycardia with complete atrioventricular dissociation probably connected with the right Mahaïm bundle].

A case of reentrant tachycardia with narrow and wide ventricular complexes without appearances of preexcitation is reported. Electrophysiological investigation showed complete retrograde atrioventricular block during tachycardia; left bundle branch block did not show the tachycardia rate. The reentry loop probably comprised: the His bundle, the right bundle branch, a right Mahaïm bundle and possibly a myocardial bridge. Possible intra-hisian reentry is discussed. The initiation of the tachycardia is analysed together with the possible consequences of permanent cardiac pacing.

Bundle of His↗
PubMed1975

[Atrial systole. Study of its role in the normal subject and in left ventricular insufficiency].

In order to study the importance of atrial systole, the authors used different stimulus modalities at the same rate; they stimulated the right ventricle, the right atrium, and the two. The haemodynamic parameters were monitored by microcatheterisation of both right and left sides. A comparative study using controls and patients with left ventricular failure showed the improvement in the haemodynamic picture which was obtained in the latter group when the atrio-ventricular sequence was correct.

Blood Pressure↗
PubMedDate not supplied

Second line pharmacological management of paroxysmal and persistent atrial fibrillation in france: a cost analysis.

OBJECTIVES: Despite optimal pharmacological treatment a large proportion of patients with atrial fibrillation (Afib) are not arrhythmia-free, and remain at risk for complications such as stroke and cardiac morbidity. If first-line treatment fails, most patients receive second-line pharmacological treatment. The emergence of new technologies aimed at restoring and maintaining sinus rhythm, such as catheter ablation techniques, has increased the interest in the economic aspects of second-line pharmacological treatment. The objective was therefore to calculate the 5-year direct medical costs of second-line pharmacological management of paroxysmal and persistent Afib in France. METHODS: The analysis was based on clinical and economic literature and the input of cardiologists-electrophysiologists. The analysis included probabilities of stroke, sudden cardiac death, other cardiac and noncardiac death, direct medical costs of drugs, follow-up and complications from the healthcare payer's perspective. Included treatment strategies were (1) rhythm control with class Ic and III antiarrhythmics and (2) rate control, consisting of digoxin combined with a beta-blocker or calcium antagonist. Both strategies included aspirin or anticoagulation therapy. RESULTS: The average total 5-year cost of Afib was 16,539 Euro (FF 108,486) per patient. The result was stable to sensitivity analysis on incidence of stroke and type of stroke prevention. The main cost drivers were follow-up visits and hospitalizations and the cost of congestive heart failure. Both items being subject to some variation, they were submitted to sensitivity analysis showing minimal 5-year costs still over 14,483 Euro (FF 95,000). CONCLUSIONS: Afib management places high demands on medical resources mainly through its complications and comorbidity.

Journal Article↗
PubMedDate not supplied

Cavotricuspid isthmus mapping to assess bidirectional block during common atrial flutter radiofrequency ablation.

BACKGROUND: We sought to compare published methods to an alternative approach ascertaining cavotricuspid isthmus (CTI) block during atrial flutter ablation. METHODS AND RESULTS: In 39 consecutive patients who underwent an atrial flutter ablation procedure, a 24-pole mapping catheter was positioned so that 2 adjacent dipoles were bracketing the targeted CTI line of block (LOB), with proximal dipoles lateral to the LOB and distal dipoles in the coronary sinus. Two pacing sites were lateral (positions A and B) and 2 were septal (positions C and D) to the LOB, with locations A and D closest to the LOB. A resulting CTI block was accepted when 3 criteria were fulfilled: (1) complete reversal of the right atrial depolarization on the 24-pole catheter when pacing in the coronary sinus, (2) conduction delays from A to D greater than from B to D, and (3) conduction delays from D to A greater than from C to A. A successful CTI block was obtained in all patients. Before CTI block was obtained, a progressive CTI conduction delay was observed in 11 patients (28.2%). During the procedure, the 3 criteria defined above were either all present or all absent. CONCLUSIONS: This study establishes that reversal of the atrial depolarization sequence up to the LOB is a definitive and mandatory criteria of successful atrial flutter ablation.

Aged↗
PubMedDate not supplied

[Ventricular extrasystole: prognostic value and therapeutic indication].

Ventricular beats are abnormal rhythms which are frequently detected by modern recording techniques in healthy subjects as well as in patients with heart disease. In the first case, analysis of the literature enables us to exclude any pejorative prognostic implication associated with V.E.B., in the absence of any major risk factor for coronary artery disease. However, when there is an underlying heart disease, a number of subgroups can be distinguished with a high risk of sudden death: coronary insufficiency associated with ischaemic cardiomyopathy, especially in the early post-hospital phase after a myocardial infarction; hypertrophic cardiomyopathy with ventricular tachycardia on the Holter monitor, family history of sudden death, personal past history of syncope; mitral prolapse with clinical symptoms and auscultatory signs; idiopathic long QT syndrome. In contrast, V.E.B.s do not appear to have prognostic significance in idiopathic hypokinetic cardiomyopathies and aortic valvular disease. In general, it is more the clinical setting than the actual morphology which determines the prognostic implications of ventricular extrasystoles. The sub-groups at high risk should be treated with anti-arrhythmics, but the evaluation of the effectiveness of such treatment remains uncertain and the authors believe that the development of studies of ventricular stimulation prior to and during treatment are justified.

Anti-Arrhythmia Agents↗
PubMedDate not supplied

[Visualization of the left coronary artery with two-dimensional echocardiography (author's transl)].

The purpose of this study was to evaluate the usefulness of two-dimensional echocardiography of the left coronary artery (LCA). This vessel could be visualized in about 80% of the patients, and its pathological features (stenosis, density, irregularities) are described. The first prospective studies seem to have demonstrated the high predictive value of this method for LCA lesions (75%). Two-dimensional echocardiography deserves to be more widely used for non-invasive exploration of patients with coronary disease.

Adult↗