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Biomedical subjects

E A Schultz

Publications and source records attributed to E A Schultz.

5 recordsLinked to original sources

Informed consent: an overview.

The patient, as a health care consumer, has a fundamental right to determine what shall be done to his or her own body. The doctrine of informed consent has evolved to protect that right. This article represents a review of the literature regarding the informed consent process in medicine, with an emphasis on consent for anesthesia. A brief history of informed consent is provided, as well as discussion of the controversies surrounding the topic. Several court cases are cited, and the opinions of various authors reflect the wide range of legal and ethical implications associated with informed consent.

Consent Forms↗

Dual role for fimbriata in regulating floral homeotic genes and cell division in Antirrhinum.

The fimbriata (fim) gene of Antirrhinum affects both the identity and arrangement of organs within the flower, and encodes a protein with an F-box motif. We show that FIM associates with a family of proteins, termed FAPs (FIM-associated proteins), that are closely related to human and yeast Skp1 proteins. These proteins form complexes with F-box-containing partners to promote protein degradation and cell cycle progression. The fap genes are expressed in inflorescence and floral meristems in a pattern that incorporates the domain of fim expression, supporting an in vivo role for a FIM-FAP complex. Analysis of a series of novel fim alleles shows that fim plays a key role in the activation of organ identity genes. In addition, fim acts in the regions between floral organs to specify the correct positioning and maintenance of morphological boundaries. Taking these results together, we propose that FIM-FAP complexes affect both gene expression and cell division, perhaps by promoting selective degradation of regulatory proteins. This may provide a mechanism by which morphological boundaries can be aligned with domains of gene expression during floral development.

Amino Acid Sequence↗

Ilionguinal-iliohypogastric nerve entrapment.

Ilionguinal-iliohypogastric nerve entrapment was described as early as 1942 as a rare but proven cause of chronic inguinal pain in patients with previous lower abdominal surgery. We describe two cases of patients who presented to the emergency care unit with complaints of chronic lower abdominal pain. Surgical histories revealed known risk factors for ilioinguinal-iliohypogastric nerve entrapment. After application of a simple bedside procedure, the diagnoses were confirmed.

Abdomen↗