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Biomedical subjects

E A Paktoris

Publications and source records attributed to E A Paktoris.

At least 19 recordsLinked to original sources

[Hepatitis B as nosocomial infection (aspects of epidemiology and prevention)].

Hepatitis B (HB) was recorded in 1478 (32.3%) of 4577 patients with acute viral hepatitis in Moscow in 1992. Half (50.6%) the patients were infected with HB virus during therapeutical and diagnostic parenteral interventions in 66.1% of them at hospitals, in 7.5% during transfusions of blood and its components (at hospitals too) in the others via natural routes. The HB morbidity per 100,000 patients treated in some Moscow one-profile hospitals sharply differed (74.2 to 89.6 at one hospitals and 5.9 to 7.6% at others). The high HB morbidity at some Moscow hospitals, the group incidence of the disease were associated with the inadequate sterilization quality of medical and laboratory instruments, with the shortage of expendable instruments. The implementation of a complex of measures at individual hospitals, which were aimed at stopping the artificial HB virus transmission routes resulted in 8.2-11.7%-reductions in HB morbidity rates among the patients treated there. In 1990-1992 the HB morbidity among Moscow medical staff was 3.0-3.5-fold than among adults of the city. Surgeons, reanimatologists, and laboratory personnel more frequently fell ill. HB vaccination should be high-priority among this contingent.

Adolescent↗

[Risk of hepatitis infection of the recipients of blood from donors with HBs-antigenemia].

Observations were made on 100 recipients of blood from 40 donors with HBs-antigenemia and 106 recipients of the control group, who had received 570 ampules of blood from 491 donors, and 499 ampules from 400 donors, respectively. The incidence of post-transfusion serum hepatitis in the icteric forms was 12.7% and 1.9%, respectively (P less than 0.002), varying between 8.9% and 22.2% in the experimental subgroups, and decreasing with the increase of the total number of blood transfusions received by the subjects. The source of infection proved to be 0.5% of the donors in the control group, and 2.65% in the experimental group (P less than 0.01), or 17.9-33.3%, of donors with HBs-antigenemia. With the sufficient number of recipients traced to each donor, all donors with HBs-antigenemia were found to be the sources of infection. It means that HBs-antigenemia may be regarded as the indication of the presence of the complete (infective) hepatitis virus B in the body.

Blood Donors↗