Reversible covalent chemistry of CO2.
Reversible reaction of CO2 with fluorescently active amines in polar aprotic solvent rapidly results in carbamic acids, which significantly enhances the solution fluorescence.
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Biomedical subjects
Dmitry M Rudkevich
Publications and source records attributed to Dmitry M Rudkevich.
Chemical amplification with encapsulated reagents.
Autocatalysis and chemical amplification are characteristic properties of living systems, and they give rise to behaviors such as increased sensitivity, responsiveness, and self-replication. Here we report a synthetic system in which a unique form of compartmentalization leads to nonlinear, autocatalytic behavior. The compartment is a reversibly formed capsule in which a reagent is sequestered. Reaction products displace the reagent from the capsule into solution and the reaction rate is accelerated. The resulting self-regulation is sensitive to the highly selective molecular recognition properties of the capsule.
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Amplification by compartmentalization.
Autocatalysis and chemical amplification are properties of living systems that can lead to increased responsiveness and to self-replication. Here we describe a synthetic system in which a unique form of reagent compartmentalization gives rise to nonlinear kinetics that are subject to the precise size- and shape-selectivity of the host. The reactivity is reminiscent of autocatalytic behaviour, in which there is no direct contact between reagents and products, and our approach offers a general way to impose complex chemical behaviour onto synthetic systems.
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