Visual diagnosis: a 9-year-old girl who has fever, headache, and right eye pain.
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Biomedical subjects
Publications and source records attributed to Deepak Kamat.
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International travel by children is becoming increasingly common over the last few decades. As a result, clinicians may be asked to assist in the evaluation and treatment of an ill child after international travel. Along with recording the typical thorough history of present illness and medical history, the physician who cares for a child in this situation will have to take a thorough travel history and consider not only local conditions, but also possible pathogens that the child may have encountered during the journey. A detailed travel history should be routinely performed to investigate specific exposures. Reference materials are available that can guide the clinician in determining which infectious agents are endemic to various areas of the world. With the exception of obtaining a basic laboratory screen, further evaluation of the young patient should be dictated by the most likely cause of the illness. Repeated testing and examinations and close follow-up may be necessary to arrive at the proper diagnosis and initiate appropriate treatment in a timely manner.
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Malaria is a devastating disease, inflicting epidemic morbidity and mortality with an estimated 500 million cases and 2.5 million deaths annually. Children suffer the most severe morbidity; one child dies of malaria every 30 seconds, accounting for over 1 million of the deaths annually. There continues to be a tremendous increase in human migration and travel between malaria endemic and nonendemic areas, with approximately 20% of imported malaria cases to Europe and the United States occurring in children. Although many recent advances in the prevention, diagnosis, and treatment of malaria have been made, the emergence of drug resistance and changes in the disease's epidemiology present new challenges. This article discusses the special considerations encountered in the prevention and treatment of malaria in children.
A 14-year-old boy with Satoyoshi syndrome is reported. Less than 50 patients with Satoyoshi syndrome have been reported in the world literature. This patient had alopecia, muscle spasms, and skeletal abnormalities, which are three of the most common clinical features of Satoyoshi syndrome. Despite extensive laboratory evaluation, an alternate explanation was not documented for the cluster of clinical findings in this patient. Immune dysregulation is believed to be an underlying mechanism for the development of Satoyoshi syndrome. In contrast to some reports, this patient failed to respond to intravenous immunoglobulin therapy. However, he responded dramatically to steroids.
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Frequently clinicians are faced with screening and providing preventive care to immigrants, refugees, and international adoptees. Evidence-based medicine on which to base screening protocols for these populations is lacking. It is important to review all health and vaccination records of the patient. In addition to acute symptoms, one should inquire about the symptoms of diseases prevalent in the country of origin or transit (e.g., hematuria). Many unexpected pathologic conditions may be detected by a thorough physical examination. If a reliable immunization record is presented, one need not repeat the vaccines or check titers. Remaining vaccines should be administered according to ACIP guidelines, except for certain populations (e.g., adoptees). Routine laboratory screening tests should include CBC with differential, stool for ova and parasites, urinalysis, general chemistry profile, serology for hepatitis B, and tests for HIV and syphilis. A tuberculin skin test should be performed on all immigrants, and a chest radiograph should be obtained for any patient with symptoms or a positive PPD. Lead level, hepatitis C, and TSH should be obtained for all children and most adoptees. In addition, special screening tests (e.g., for malaria, hepatitis C, and STIs) may be indicated in high-risk populations. A more organized screening system that emphasizes evidence-based and population-specific screening protocols and better communication between international, federal, state, and local levels is needed in the United States.
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Perinatal clavicle fractures typically heal without complication, and subsequent refracture of the same clavicle during infancy or toddlerhood has not been reported. This is a case report of a fracture of the clavicle in a 9-month-old child who had previously suffered a fracture of the same clavicle at birth. A review of the evaluation and management of neonatal and post-neonatal clavicle fractures is also presented.
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