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Biomedical subjects

David L Roberts

Publications and source records attributed to David L Roberts.

14 recordsLinked to original sources

The functional significance of social cognition in schizophrenia: a review.

Deficits in a wide array of functional outcome areas (eg, social functioning, social skills, independent living skills, etc) are marked in schizophrenia. Consequently, much recent research has attempted to identify factors that may contribute to functional outcome; social cognition is one such domain. The purpose of this article is to review research examining the relationship between social cognition and functional outcome. Comprehensive searches of PsycINFO and MEDLINE/PUBMED were conducted to identify relevant published manuscripts to include in the current review. It is concluded that the relationship between social cognition and functional outcome depends on the specific domains of each construct examined; however, it can generally be concluded that there are clear and consistent relationships between aspects of functional outcome and social cognition. These findings are discussed in light of treatment implications for schizophrenia.

Affect↗

On the Pleistocene extinctions of Alaskan mammoths and horses.

The fossil record has been used to shed light on the late Pleistocene megafaunal extinctions in North America and elsewhere. It is therefore important to account for variability due to the incompleteness of the fossil record and error in dating fossil remains. Here, a joint confidence region for the extinction times of horses and mammoths in Alaska is constructed. The results suggest that a prior claim that the extinction of horses preceded the arrival of humans cannot be made with confidence.

Alaska↗

Six sessions of manual therapy increase knee flexion and improve activity in people with anterior knee pain: a randomised controlled trial.

QUESTION: What are the effects of manual therapy on pain, range of motion, and activity in patients with anterior knee pain? DESIGN: Randomised controlled trial. PARTICIPANTS: Thirty-eight ambulatory care patients (one dropout) with anterior knee pain. INTERVENTION: The experimental intervention consisted of six sessions of manual therapy, while the control intervention was to remain on the waiting list for two weeks. OUTCOME MEASURES: Pain was measured using the Patellofemoral Pain Severity Questionnaire. Active knee flexion and extension was measured from photographs. Activity was measured by having the participants step up and down a 15 cm step, leading with the painful leg as many times as they could in a 60 second period. Measurements were taken before and after intervention by a blinded assessor. RESULTS: The experimental group decreased their pain by -8 mm (95% CI to 1 p =0.08) and pain on stairs by-10, (95% CI -22 to 2 p = 0.10) compared with the control group. They increased their active knee flexion by 10 deg (95% CI TO 16, p = 0.004) and and the number of steps in 60 seconds by 5 (95% CI 2 TO 8, p = 0.001) compared with the control group. CONCLUSION: Manual therapy is effective improving knee flexion and stair climbing i patients with anterior knee pain. There is a trend towards a small improvement in pain.

Adolescent↗

Do baseline client characteristics predict the therapeutic alliance in the treatment of schizophrenia?

This study examined clinical predictors of client and therapist alliance ratings early in therapy, the relationship between client and therapist alliance ratings, and the psychometric properties of the Working Alliance Inventory in individuals with schizophrenia receiving manual-based treatment. Assessment of clinical symptoms and social functioning were conducted at baseline, and alliance ratings were obtained at 5 weeks. The Working Alliance Inventory had high internal consistency, but there were low correlations between client and therapist ratings. Results also indicated that social functioning and the activation and autistic preoccupation factors on the Positive and Negative Syndrome Scale were significant predictors of therapists' alliance ratings. There were no significant relationships between clinical predictors and clients' therapeutic alliance ratings. The findings indicate that client interpersonal factors are significant predictors of the therapist-rated alliance in the treatment of schizophrenia. Low correlations between clients' and therapists' ratings of the alliance should be examined in future research.

Adult↗

Significance of sighting rate in inferring extinction and threat.

We are now entering a time of immense environmental upheaval in which, increasingly, experts are required to provide conservation assessments. Quantitative assessment of trends in species' range and abundance is costly, requiring extensive field studies over a long period of time. Unfortunately, many species are only known through a few "chance" sightings or a handful of specimens, and therefore extinction may be even harder to ascertain. Several methods have been proposed for estimating the probability of extinction. However comparison within and between species is difficult because of variations in sighting rates. We applied a probabilistic method that incorporates sighting rate to the sighting record of Vietnamese slipper orchids (Paphiopedilum). The method generates a probability that another sighting will occur given the previous sighting rate and the time since last observation. This allows greater comparability between species discovered at different times. Its predictions were more highly correlated with the World Conservation Union criteria than previous methods. Trends in data collection and the political climate of a country, which affects access to material, are important potential sources of variation that affect sighting rates. A lack of understanding of the process by which data are generated makes inferring extinction from sighting records difficult because extinction status depends on how the sighting rate varies. However such methods allow rapid conservation prioritization of taxa that are poorly known and would otherwise go unassessed.

Conservation of Natural Resources↗

Routine chest radiography in a primary care setting.

PURPOSE: To determine the frequency, diagnostic yield, outcomes, cost, and rate of false-positive results of routine chest radiography performed in asymptomatic patients in the primary care setting. MATERIALS AND METHODS: Radiography reports on all patients who underwent routine or screening posteroanterior and lateral chest radiography at a university-affiliated primary care clinic in 2001 were reviewed. Radiographic results were coded as normal or minor findings or as major abnormalities, such as pulmonary nodules, requiring further diagnostic evaluation. Outcomes of patients with major abnormalities were established by using chart reviews or reviewing additional radiographs. Costs were estimated by using 2002 Medicare reimbursement rates. The main measures assessed were frequency, costs, and rate of false-positive results of routine chest radiography. RESULTS: Of 3812 radiographs obtained at the primary care clinic, 1282 (34%) were ordered for routine or screening purposes by the referring physician. Nine hundred twenty-two radiographs were obtained in male patients and 360 were obtained in female patients; their mean and median age was 49 years (age range, 4-87 years). Fifteen chest radiographs showed major abnormalities. No patient younger than 40 years had a major abnormality. Fourteen of the 15 findings of major abnormalities proved to be false-positive. No disease requiring treatment was diagnosed as a result of radiographic findings. The total cost for follow-up radiography and computed tomography was US dollar 46,609.49. CONCLUSION: Routine chest radiography has low diagnostic yield in asymptomatic primary care patients.

Adolescent↗

Jail linkage assertive community treatment services for individuals with mental illnesses.

Persons with mental illnesses who are released from jail or prison are at high risk of psychiatric decompensation and re-arrest. This paper describes an ACT jail linkage program for this population that won an American Psychiatric Association Gold Award (2001). Based on interviews with its first 24 participants, we illustrate how they experience factors that contribute to recidivism and decompensation. Pre- and post-data are examined to explore program outcomes. Results suggest that it is possible to identify, engage, and retain people in treatment who struggle with many risk factors. We conclude that this program should be expanded and replicated.

Adult↗

Flightless birds: when did the dodo become extinct?

The extinction of the dodo (Raphus cucullatus L.; Fig. 1) is commonly dated to the last confirmed sighting in 1662, reported by Volkert Evertsz on an islet off Mauritius. By this time, the dodo had become extremely rare - the previous sighting having been 24 years earlier - but the species probably persisted unseen beyond this date. Here we use a statistical method to establish the actual extinction time of the dodo as 1690, almost 30 years after its most recent sighting.

Animals↗

A trial into the effectiveness of soft tissue massage in the treatment of shoulder pain.

The purpose of this single blinded randomised controlled trial was to investigate the effects of soft tissue massage on range of motion, reported pain and reported function in patients with shoulder pain. Twenty-nine patients referred to physiotherapy for shoulder pain were randomly assigned to a treatment group that received six treatments of soft tissue massage around the shoulder (n = 15) or to a control group that received no treatment while on the waiting list for two weeks (n = 14). Measurements were taken both before and after the experimental period by a blinded assessor. Active range of motion was measured for flexion, abduction and hand-behind-back movements. Pain was assessed with the Short Form McGill Pain Questionnaire (SFMPQ) and functional ability was assessed with the Patient Specific Functional Disability Measure (PSFDM). The treatment group showed significant improvements in range of motion compared with the control group for abduction (mean 42.2 degrees, 95% CI 24.1 to 60.4 degrees), flexion (mean 22.6 degrees, 95% CI 12.4 to 32.8 degrees) and hand-behind-back (mean 11.0 cm improvement, 95% CI 6.3 to 15.6 cm). Massage reduced pain as reported on the descriptive section of the SFMPQ by a mean of 4.9 points (95% CI 2.5 to 7.2 points) and on the visual analogue scale by an average of 26.5 mm (95% CI 5.3 to 47.6 mm), and it improved reported function on the PSFDM by a mean of 8.6 points (95% CI 4.9 to 12.3 points). We conclude that soft tissue massage around the shoulder is effective in improving range of motion, pain and function in patients with shoulder pain. The mechanisms behind these effects remain unclear.

Adult↗

Representative payeeship and mental illness: a review.

Representative Payeeship (RP) is intended to help individuals who are unable to manage disability payments appropriately to meet their basic living needs. This paper reviews the literature on whether RP is effective among individuals with mental disorders. We also review RP's mental health effects and its use as leverage in achieving behavioral goals. RP appears to be effective in helping clients meet their basic living needs; it also may decrease hospitalization and improve treatment compliance. Finally, we propose a research design to disentangle the role of clinical leverage from the more basic money-management function of RP.

Consumer Behavior↗

Expert guidelines for the treatment of severe PMS, PMDD, and comorbidities: the role of SSRIs.

The hallmark feature of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) is the predictable, cyclic nature of symptoms or distinct on/offness that begins in the late luteal phase of the menstrual cycle and remits shortly after the onset of menstruation. PMDD is distinguished from PMS by the severity of symptoms, predominance of mood symptoms, and role dysfunction, particularly in personal relationships and marital/family domains. Several treatment modalities are beneficial in PMDD and severe PMS, but the selective serotonin reuptake inhibitors (SSRIs) have emerged as first-line therapy. The SSRIs can be administered continuously throughout the entire month, intermittently from ovulation to the onset of menstruation, or semi-intermittently with dosage increases during the late luteal phase. These guidelines present practical treatment algorithms for the use of SSRIs in women with pure PMDD or severe PMS, PMDD and underlying subsyndromal clinical features of mood or anxiety, or premenstrual exacerbation of a mood/anxiety disorder.

Anxiety↗