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Biomedical subjects

Dave Roberts

Publications and source records attributed to Dave Roberts.

8 recordsLinked to original sources
PubMed2006

Redescriptions of two marine planktonic ciliates from China, Parastrombidium faurei (Kahl, 1932) Maeda, 1986 and Strombidium capitatum (Leegaard, 1915) Kahl, 1932 (Ciliophora, Oligotrichea).

The morphology and infraciliature of two marine planktonic ciliates, Parastrombidium faurei (Kahl, 1932) Maeda, 1986 and Strombidium capitatum (Leegaard, 1915) Kahl, 1932, from coastal waters near Qingdao (Tsingtao), northern China, were investigated based on live observation and protargol impregnation. This is the first time that these two species are reported from Yellow Sea/North Pacific. Emended diagnoses for the genus Parastrombidium and its single species P. faurei are provided as they were not studied with modern methods before. The ciliary pattern and the stomatogenesis of Parastrombidium indicate that it belongs to the order Choreotrichida Small and Lynn, 1985, family Strombidinopsidae Small and Lynn, 1985. An updated description for the "well-known"Strombidium capitatum is also included based on the Qingdao population.

Animals↗
PubMed2006

Intertumoural variability in functional imaging within patients suffering from neuroendocrine tumours. An observational, cross-sectional study.

(123)I mIBG (meta-iodobenzylguanidine) and (111)In pentetreotide scintigraphy imaging modalities are useful in demonstrating neuroendocrine tumours. Although (111)In pentetreotide is generally held to be a more superior imaging agent than (123)I mIBG for neuroendocrine tumours, we noted a differential uptake of the two agents by different tumour sites within individual patients. In some cases, the two tracers appeared to demonstrate different lesions within the same patient. The aim of this study wasto determine the positivity of the two imaging modalities, the degree of correlation between them and to highlight any clinically useful differences between the two modalities. (123)I mIBG and (111)In pentetreotide images of 149 consecutive, biopsy-proven or biochemically confirmed, neuroendocrine tumour patients were compared. All the patients underwent whole-body imaging and upper abdominal single-photon emission computed tomography (SPECT). The results of both types of imaging were compared, lesion by lesion, for each individual patient. The overall positivity rate for (111)In pentetreotide was 79%, and that for (123)I mIBG was 63%. When both agents were positive, the (111)In pentetreotide highlighted more lesions within the same patient in 33%, whilst the (123)I mIBG highlighted more lesions in 13%. In 12% of patients both agents were positive, but different lesions were seen with the two agents. (111)In pentetreotide has greater positivity than (123)I mIBG for imaging neuroendocrine tumours. However, the two modalities can highlight different tumour lesions, suggesting the presence of phenotypically diverse tumour populations within individual patients. These findings are likely to influence clinical management in the future.

3-Iodobenzylguanidine↗
PubMed2003

Leading lights.

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Administrative Personnel↗
PubMed2003

Virtual reality and interactive 3D as effective tools for medical training.

CAVE-like displays allow a user to walk in to a virtual environment, and use natural movement to change the viewpoint of virtual objects which they can manipulate with a hand held device. This maps well to many surgical procedures offering strong potential for training and planning. These devices may be networked together allowing geographically remote users to share the interactive experience. This maps to the strong need for distance training and planning of surgeons. Our paper shows how the properties of a CAVE-Like facility can be maximised in order to provide an ideal environment for medical training. The implementation of a large 3D-eye is described. The resulting application is that of an eye that can be manipulated and examined by trainee medics under the guidance of a medical expert. The progression and effects of different ailments can be illustrated and corrective procedures, demonstrated.

Computer Simulation↗