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Biomedical subjects

D du Toit

Publications and source records attributed to D du Toit.

11 recordsLinked to original sources
PubMed1989

Seminal carnitine, epididymal function and spermatozoal motility.

The carnitine content of semen from azoospermic subjects and subjects with either impaired motility or forward progression is reported. Within the azoospermic group, the values were not significantly different between those with testicular failure or obstruction. The patients with impaired motility (less than 40%) or impaired forward progression (less than 3) had a lower mean seminal carnitine content than those with good motility and forward progression (P less than 0.05). Seminal carnitine concentration was not an index of epididymal patency and could not be regarded as useful for locating the level of obstruction in the epididymis. Since carnitine plays an important role in the maturation process when sperm acquire motility, it would seem that seminal carnitine might be an indicator of epididymal dysfunction.

Carnitine↗
PubMed1986

[Stress!].

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Adaptation, Psychological↗
PubMedDate not supplied

Impaired epididymal function in patients with detached ciliary tufts in semen: a preliminary report.

Low spermatozoal ATP concentration in the presence of high alpha-glucosidase activity may indicate efficient epididymal function. It was suggested that detached ciliary tufts (DCTs) originated from the epididymis. We compared the spermatozoal ATP concentration and alpha-glucosidase activity in semen of patients with DCTs to that of a control group. Higher ATP concentration and lower alpha-glucosidase activity were found in patients with DCTs in their semen compared to the control group. These results might probably point out impaired epididymal function and further support the proposed epididymal origin of these tufts.

Adenosine Triphosphate↗
PubMedDate not supplied

alpha-Glucosidase, sperm ATP concentrations, and epididymal function.

It has been suggested that alpha-glucosidase may be a marker of epididymal patency and function. Spermatozoal ATP concentrations decrease during passage through the epididymis, indicating efficient maturation. We correlated sperm motility with seminal plasma alpha-glucosidase activity and spermatozoal ATP. The sperm motility correlation with alpha-glucosidase activity was significantly positive, and the sperm motility correlation with spermatozoal ATP was significantly negative. It appears that high-alpha-glucosidase activity and low-spermatozoal ATP were present in semen with good sperm motility and could possibly indicate efficient epididymal function.

Adenosine Triphosphate↗
PubMedDate not supplied

High seminal sialic acid concentrations in patients with severe teratozoospermia.

Seminal plasma and sperm-bound sialic acid (SA) concentrations were evaluated in patients with severe teratozoospermia (less than 5% morphologically normal sperm) and correlated with values of a control group with greater than 20% morphologically normal sperm. The SA concentrations both in seminal plasma and on sperm were significantly higher in teratozoospermia, but the ratio of sperm-bound SA to seminal plasma SA remained virtually the same. The causes and consequences of high SA in these patients need further study.

Humans↗