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Biomedical subjects

D Zdravkovic

Publications and source records attributed to D Zdravkovic.

At least 19 recordsLinked to original sources
PubMed1996

MRI evaluation of the knee in rheumatoid arthritis.

The knees of forty-three patients suffering from rheumatoid arthritis (RA) were examined using pre- and post-contrast MRI in an attempt to assess the extent and frequency of all abnormalities in the RA knee. Features evaluated by MRI were: synovial thickening, joint effusion, bone destruction, popliteal cysts, periarticular soft tissue swelling, abnormal tendons and bone marrow changes. A scoring system (0-2) was used to determine the relationship between the various signs of RA in order to identify those that may be relevant for the assessment of therapeutic response. It seems that the assessment of inflamed synovium is the major criterion for the determination of disease activity in RA.

Arthritis, Rheumatoid↗
PubMed1993

Magnetic resonance imaging of bone destruction in rheumatoid arthritis: comparison with radiography.

Bony changes in forty-four knees of patients with clinically established rheumatoid arthritis (RA) were examined using magnetic resonance imaging (MRI) and plain film radiography. In all cases MRI was clearly superior to radiographs, demonstrating 25 marginal erosions and 42 subchondral cysts, while the number seen on radiographs was 3 and 8, respectively. These results emphasize the problems in visualizing bone erosions in large joints using plain films. MRI is the method of choice for detecting early changes in RA, not only because of its high sensitivity, but also because of the ability of contrast-enhanced MRI to provide physiological characterization of these lesions.

Adult↗
PubMed1987

Changes in serum ferritin following surgical trauma.

A statistically significant increase in serum ferritin values was found in 14 male patients already 1 d after uniform operative trauma and, on the 3rd d following operation, the last day of observation period values were still increased. Moreover, in all patients a highly significant fall in plasma iron of acute onset was found. The hypoferremia was already seen on the day after operation. Serum transferrin was also found to be significantly reduced after operation.

Adult↗
PubMed1981

Complications following osteotomy of the greater trochanter in total hip replacement arthroplasty using the lateral approach.

In a consecutive series of 365 hip replacement arthroplasties ad modum Charnley in 309 patients migration of the trochanteric fragment was encountered in 4.9 per cent of the cases. The predisposing factors were wire-breakage, trochanteric fractures and excessive weight. Men were more apt than women to develop migration. Early mobilization with weight-bearing on the operated leg did not increase the risk of migration. The migration rarely gave rise to complaints, and if so only mild ones. Trochanteric union did not pose problems, and at the end of 2 years 98 per cent had united. After 5 years no case of non-union was detected.

Adult↗
PubMed1980

Ectopic bone formation following Charnley hip arthroplasty.

In a consecutive series of 309 patients the degree of ectopic bone formation was assessed 3 months, 2 years, and 5 years after total hip arthroplasty. At the three follow-up examinations ectopic bone formation was found in 49 per cent, 61 per cent, and 71 per cent. In men ectopic bone formation was more common and more pronounced than in women. It was demonstrated that walking ability and range of hip movement may be reduced in the presence of ectopic bone formation. A past history of hip surgery, preoperative exostoses, and postoperative elevation of the erythrocyte sedimentation rate did not appear to influence the formation of ectopic bone. There was no correlation between the degree of ectopic bone formation in the two hips of patients who had undergone bilateral operation. In the present study it was not possible to demonstrate preoperatively which groups of patients are most liable to develop ectopic bone postoperatively.

Adult↗
PubMed1978

Quadriceps function following indirect nailing of femoral shaft fractures.

A series of 24 adult patients with isolated, unilateral fractures of the femoral shaft treated by indirect Street-Hansen nailing is submitted. Follow-up included clinical and radiological assessment as well as measurement of quadriceps power. Isometric strength as well as dynamic endurance were significantly decreased at the 5 per cent level as compared with the unaffected leg. There was a poor correlation between thigh circumference and strength. The decrease in strength and endurance after indirect nailing was less than that found in previous investigations of femoral fractures treated by direct nailing.

Adolescent↗