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Biomedical subjects

D Zanuttini

Publications and source records attributed to D Zanuttini.

At least 91 records · Page 5Linked to original sources
PubMed1985

[Possibilities and difficulties of differential diagnosis by 2-dimensional echocardiography of mobile masses inside the right atrium. Apropos of a case].

A peculiar case of mobile right atrial mass thrombotic in origin identified by two-dimensional echocardiography is reported. By the characteristics of the mass and the negative history for SBE and malignant neoplasm, the possibilities of tricuspid vegetations or infiltration by an extracardiac tumor could be reasonably ruled out. On the other hand, a myxomatous mass could not be excluded in this case. The thrombotic nature of the mass was recognized at autopsy. The possibility to identify by two-dimensional echocardiography right atrial masses together with the difficulties in certain particular cases to recognize their nature are discussed.

Aged↗
PubMed1984

Prospective identification of patients with amyloid heart disease by two-dimensional echocardiography.

The purpose of this study was to determine whether changes in myocardial wall echogenicity that suggest amyloid disease could be prospectively identified by a qualitative analysis of two-dimensional echocardiographic images. Two thousand seventy-eight consecutive echocardiograms obtained over a 14 month period were prospectively analyzed. The myocardial walls of 30 patients showed multiple, discrete, small highly refractive echoes; amyloid disease was not known or suspected in any of them. It was recommended that all 30 patients undergo gingival biopsy to confirm the diagnosis and biopsy was performed in 15 patients. The recommendation for biopsy was made only on the basis of two-dimensional echocardiographic images and was independent of findings regarding thickness of the walls or the dimensions of the cardiac chambers. Results of biopsy were positive in 11 patients and negative in four. We conclude that qualitative evaluation of two-dimensional echocardiographic images can identify changes in myocardial wall echogenicity that correlate with a result of gingival biopsy positive for amyloidosis. In patients who have a typical myocardial texture by two-dimensional echocardiography and a positive gingival biopsy result, cardiac amyloidosis should be strongly suspected.

Adult↗
PubMed1984

In vivo and in vitro evaluation of left ventricular thrombi by two-dimensional echocardiography. Comparison with cineventriculography.

The purpose of this study was to assess the capability of two-dimensional echocardiography to identify left ventricular thrombi as compared to standard single plane cineventriculography in 284 patients, who underwent both procedures within 24 hours for diagnostic purposes. In order to obtain informations about the degree of thrombus organization and diagnostic accuracy of the echocardiographic technique, two-dimensional echocardiographic examinations were also performed in 31 thrombi from 16 autopsy specimens. In 249 cases the results were negative and in 14 cases positive by both techniques. Seven cases were positive by cineventriculography but negative by 2D-echocardiography. In seven cases the findings were equivocal by two-dimensional echocardiography; three of them were negative, two positive, and two equivocal by cineventriculography. In two cases the results were negative by two-dimensional echocardiography but equivocal by cineventriculography. Finally five cases were diagnosed to have a thrombus but two-dimensional echocardiography but not by cineventriculography. In two patients, positive by two-dimensional echocardiography, who were on anticoagulant therapy, follow-up studies showed the disappearance of left ventricular thrombi. In all of them the thrombi showed tissue characteristics similar to those of fresh thrombi examined in vitro. Two-dimensional echocardiography seems to be more reliable than cineventriculography for assessing the presence, extension, number, and morphology of left ventricular thrombi. In vitro studies suggest that two-dimensional echocardiography cannot visualize small thrombi, that fibrotic areas may simulate a thrombus and that in some cases under or overestimation is possible.

Adolescent↗
PubMed1984

[Echocardiographic documentation of fibrocalcific degenerative changes of a lascia lata valvular prosthesis at the aortic valve].

The echocardiographic features of fibrocalcific degeneration of fascia lata aortic bioprosthesis are presented in two cases. M-Mode and 2D echocardiograms showed increased density and reduced motion of the bioprosthetic leaflets, suggestive of fibrocalcific degeneration. These features were confirmed at surgery. Two-dimensional echocardiography was mostly useful (in one case) in the assessment of morphology and motion of the diseased prosthetic valve.

Adult↗
PubMed1982

M-mode and two-dimensional echocardiography in congenital absence of the pericardium.

The M-mode and two-dimensional echocardiographic features of congenital absence of the pericardium are described in two cases that had been confirmed by clinical and radiological data. The M-mode echocardiogram showed right ventricular dilatation and abnormal systolic motion of the interventricular septum. Echo contrast studies with peripheral injection of saline solution revealed normal persistence of microbubbles in the right side of the heart. Two-dimensional short axis parasternal views showed some dilatation of the right ventricle, with anterior displacement of the left ventricular cavity in systole, which appeared to be wider than the posterior motion of the interventricular septum towards the posterior wall. The resulting positive motion of the interventricular septum toward the transducer could account for the abnormal pattern seen in the M-mode echocardiogram. Congenital absence of the left pericardium has particular echocardiographic features not diagnostic for the anomaly. However, the M-mode and two-dimensional echocardiographic studies, used in conjunction with the echocontrast techniques, seem to help in the differential diagnosis and for excluding associated anomalies.

Adult↗
PubMed1981

Progression of aortic root dissection and cardiac tamponade. Documented by sequential echocardiographic examinations.

The M-mode echocardiographic features of aortic root dissection and its progression to cardiac tamponade in a 68-year-old white man are reported. The diagnosis was confirmed both by angiography and by autopsy. Negative and positive echocardiographic patterns could be obtained at the time of the first clinical diagnosis with slight different angulations of the transducer. Progression of the dissection and evidence of increase of pericardial fluid to cardiac tamponade could then be documented by sequential echocardiograms. M-mode echocardiography is a useful tool in the recognition of aortic dissection. Prolonged and accurate searching of the dissected area is required before a negative echocardiogram is accepted. Multiple sequential echocardiograms must be obtained to eventually detect a progression of the dissection or an increase in pericardial fluid. The possibility to follow the evolution of the disease may be extremely important in the choice of therapeutic intervention.

Aged↗
PubMed1980

Large right atrial thrombosis. Rare complication during permanent transvenous endocardial pacing.

Right atrial thrombosis is a rare complication of permanent endocardial pacing. We report two cases with large right atrial thrombi which occurred during permanent endocardial electrical stimulation. Both patients were women, aged 83 and 89 years, who died suddenly, respectively, one month and 24 days after pacemaker implantation. At the time of death the two patients were in severe persistent refractory congestive heart failure despite appropriate medical treatment. At necropsy large mobile right atrial thrombi were found in both cases.

Aged↗
PubMed1979

[Hypoxic pulmonary vasoconstriction and angiotensin II blockade in calves (author's transl)].

The pulmonary vascular response to breathing low oxygen containing gas mixture was examined before and during Angiotensin II blockade in five open-chested newborn calves. Angiotensin II blockade was achieved by continuous infusion of Sar1-Ile5-Leu8-Angiotensin II (Saralasin), a competitive inhibitor of Angiotensin II. The hypoxic rise in pulmonary vascular resistance after blockade did not differ from that of control. It is concluded that Angiotensin II does not play a significant role in acute hypoxic pulmonary vasoconstriction in the calf.

Angiotensin II↗
PubMed1978

[A regional experience with permanent cardiac pacing: in Friuli-Venezia Giulia the highest density of pacemaker patients in Italy, to-day (author's transl)].

In Friuli-Venezia Giulia, a region of 1,243,463 inhabitants, a total of 1,629 first implants have been carried out since the first patient was treated with permanent cardiac pacing (P.C.P.) early in 1692. This patient is still alive. In the last four years, the annual rate of implants was 185 per million inhabitants. The average age of patients is 72.9. The most frequent indication for pacing is the a-v block (64.5%), followed by the fascicular blocks (10.8%) and the sick sinus syndrome. No asinchronous fixed rate generators are implanted at present; lithium batteries are the power source of choice to-day. There have been 1,120 replacements in the Region, mainly due to battery depletion (89.9% of cases). A total of 442 patient deaths have occurred in 10 years due to neoplasms (17%), cerebrovascular accidents (15.6%), respiratory infections (15%), myocardial infarction (8%) and other causes. In 8.8% of cases the death was sudden. There are 1,179 patients in follow-up in the Region (948 per million inhabitants). A computer system, described elsewhere in these proceedings, allows a close follow-up of these patients along with the evaluation of long term pacing on a reliable statistical basis.

Adolescent↗