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Biomedical subjects

D Zani

Publications and source records attributed to D Zani.

5 recordsLinked to original sources
PubMed2005

[Fluorescence endoscopy in the diagnosis and treatment of superficial bladder neoplasms].

AIM: The results of a clinical investigation on neoplasm and bladder dysplasia detection by 5-aminolaevulinic acid (5-ALA)-induced fluorescence are reported. In this paper the authors report their experience with 5-ALA in the diagnosis, treatment and follow-up of bladder neoplasms after chemotherapy and endocavitary immunotherapy. METHODS: The 5-ALA was instilled in the bladder 2 h before bladder transurethral resection. This method has been used since December 2000 on 163 patients and a total of 266 biopsies were histologically examined. RESULTS: One-hundred and four benign and 92 malignant/dysplastic areas were biopsied; 46 malignant/dysplastic lesions were not detected during routine white-light cystoscopy but were identified with fluorescence cystoscopy. Sensitivity was 99% but specificity was low (20%). CONCLUSIONS: ALA-based fluorescence cystoscopy is a safe and simple technique that enhances the detection of flat and papillary urothelial neoplasms.

Adult↗
PubMed1997

[Conservative therapy of renal parenchymal neoplasia].

We review our overall experience in 1375 patients, who underwent surgery for renal cell carcinoma in the Departments of Urology of Brescia and Bergamo from 1983 to 1996. 185 (13.4%) patients had nephron-sparing surgery: imperative procedure was performed in 74 cases, while an elective surgery was done in 111 patients. Three years minimal follow up was considered in order to evaluate the outcome of surgical treatment in 48 patients who underwent imperative nephron-sparing surgery and in 73 with an elective procedure. Disease specific survival was 80.8% in the first group and it was 97% in the latter.

Adult↗
PubMed1996

[Urodynamic evaluation of replacement bladders (Mainz)].

42 ileo-colonic orthotopic reservoirs (M.A.I.N.Z.) following radical cystectomy were evaluated with urodynamic studies. Long term results in 19 patients with a follow up longer than 36 months were compared to the findings of 23 patients with a shorter follow-up. Urodynamic evaluation showed a reservoir with large capacity and low pressure in both groups. Nocturnal incontinence occasionally occurred. Many factors may account for this problem. Instillation of hyperosmotic solution during cystometry resulted in increased amplitudes and frequency of intracavitary pressure waves: the nocturnal increase in urine osmolality could be in correlation with nocturnal incontinence.

Adult↗