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Biomedical subjects

D Winkle

Publications and source records attributed to D Winkle.

5 recordsLinked to original sources

Pedicle patch urethroplasty.

The pedicle patch urethroplasty provides an alternative single-stage vascularised graft procedure for the repair of moderately severe hypospadias. Over a 7-year period, 38 primary hypospadias repairs were performed employing this technique. The fistula rate was 18% in the 34 patients reviewed, but there were few other significant complications. The operation is recommended when the urethral plate can be preserved and the penis straightened in boys who are unsuitable for a meatal-based flap.

Age Factors↗

Hypospadias: Duckett pedicle tube urethroplasty.

The Duckett transverse tube pedicle urethroplasty was used to repair the primary hypospadias of 190 boys over an 11-year period. The fistula rate was 34.4%. The majority of boys have obtained a satisfactory cosmetic and functional result with a single operation.

Adolescent↗

Anaphylaxis: managing and preventing a true emergency.

Anaphylaxis is the sudden, life-threatening reaction to an antigen. It generally results from the injection of a potent antigen. However, it may be caused by the inhalation or ingestion of any antigen or allergen as well. Although anaphylaxis may occur after a single exposure to an antigen, it usually occurs after repeated exposures. There is general agreement that the sooner it occurs after exposure to the antigen, the more likely it is that the reaction will be severe. The focus of this article will be on the management and prevention of immediate hypersensitivity (anaphylaxis) induced by immunoglobulin E(IgE) or type I. Since anaphylaxis is often iatrogenic, every practitioner has a responsibility to prevent this hypersensitive state from occurring. When it does happen, prompt recognition and treatment can be lifesaving. Management needs to be initiated quickly whenever anaphylaxis seems imminent.

Anaphylaxis↗