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Biomedical subjects

D Willard

Publications and source records attributed to D Willard.

At least 145 records · Page 8Linked to original sources
PubMedDate not supplied

[Prevention of iatrogenic effects of artificial ventilation with transcutaneous monitoring of PO2 and PCO2 in the newborn infant].

The authors have monitored Tc PCO2, Tc PO2 and mean airway pressure in 25 ventilated newborns, during 68 days. They show that the best blood gases values are not even obtained with the most aggressive artificial ventilation (A.V.). Tc PCO2 and Tc PO2 transcutaneous monitoring and mean airway pressure measurement allow an "à la carte" adaptation of the A.V. to bring in each case the most efficient and the least aggressive A.V. This method may decrease the iatrogenic complications of the A.V.

Carbon Dioxide↗
PubMedDate not supplied

[Value of prealbumin in the 1st and after the 12th day of life].

From a series of 129 neonates, well defined with regard to weight and gestational age, the authors established that serum concentration of prealbumin (PA) in an aseptic neonate depends on its gestational age on the first day of extrauterine life (p less than 0.001). Serum concentrations of PA are significantly different in appropriate for gestational age (AGA) and small for gestational age (SGA) neonates; this may be the consequence of insufficient materno-foetal transfers in the majority of SGA children. The study of the ratio maternal PA/neonatal PA at the time of delivery helps to establish the cause of SGA. On and after the 12th day of life, serum concentrations of PA are closely correlated with the usual data of anthropometry (weight, height, skull circumference) (p less than 0.001), when correlation is less close with gestational age at the time of sample taking: it may be used as a marker of the appropriateness of gestational age rather than of maturity. However, the ratio PA/weight varies from one child to another and from one week to another for a same child, giving PA a value different from ordinary anthropometry for the evaluation of the appropriateness of gestational size in neonates.

Anthropometry↗
PubMedDate not supplied

[Etiology and prevention of severe mental handicaps].

In a group of 124 children with mental retardation, a study showed 21% of chromosomal abnormalities, 26% of perinatal causes and 33% of undetermined causes. Current preventive measures are well adapted. They might be usefully completed by mandatory ultrasonographic examinations during pregnancy and promotion of birth of at-risk children in well-equipped centers for perinatal medicine. In cases when in utero transfer is not possible, transfer by specialized pediatric emergency care services should be generalized. A better supervision of families where retarded children are living would be advisable. The detection of bacterial meningitis should be improved. Finally, an active research should be undertaken in order to better dissociate and understand the as yet unknown causes of mental retardation.

Adolescent↗