Search PubMed⌕ Search

Biomedical subjects

D White

Publications and source records attributed to D White.

At least 325 records · Page 18Linked to original sources
PubMed1984

Sex chromosome anomalies, hormones, and aggressivity.

This double-blind, controlled study of XYY and XXY men found in a birth cohort of 4,591 tall men born in Copenhagen assessed evidence of delinquent and aggressive behavior and explored the role of hormonal determinants in the behavioral and psychological differences noted among groups. Information from social records, a structured psychological interview, and projective tests did not support the notion that men with sex chromosome anomalies are particularly violent or aggressive. Hormonally, XYY men had significantly higher concentrations of testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) than matched control groups. In contrast, XXY men had higher levels of LH, FSH, and prolactin, but low concentrations of testosterone. There was a significantly positive relation among all subjects as well as XY controls alone between plasma testosterone level and evidence of criminal convictions. A proportionate increase in testosterone levels was noted when subjects were divided into nondelinquents, delinquents without violent convictions, and delinquents with violent convictions. The relation between testosterone level and criminal behavior was not reflected in measures of aggression derived from the psychological interview and projective tests. There was no specific evidence that testosterone is a mediating factor in the criminal behavior of XYY men.

Adult↗
PubMed1984

Angiokeratoma of Fordyce: successful treatment with the argon laser.

Argon laser photocoagulation of angiokeratomas of Fordyce, or scrotal angiomas, has been described. The benefits of the argon laser in treatment of these lesions include permanent eradication of the lesions and alleviation of the symptoms of pruritus and episodic bleeding. This method of treatment is safe, does not produce iatrogenic malignant neoplasms, is noninvasive, and is accomplished as an outpatient procedure under local anesthesia with minimal discomfort or disability.

Angiokeratoma↗
PubMed1983

Proximal gastric vagotomy: a 7-year review.

The records of 31 patients (25 men, 6 women) who had a proximal gastric vagotomy for duodenal ulcer between 1975 and 1981 were reviewed. The mean follow-up was 48 months (range from 9 to 86 months). The mean duration of symptoms was 9 years. Nine patients were treated for bleeding and one had had perforation. In nine patients, concomitant fundoplication was performed and three patients had dilatation of the pylorus. In the postoperative period, nasogastric suction was used for 1 day, full diet was given after 3 days and the hospital stay was 6 days on average. Two patients (6.5%) probably had recurrence, but only one underwent investigation. Postoperative symptoms were generally mild and transient. Two patients described late dumping and four had early satiety. None thought these symptoms were very important. Diarrhea and weight loss were not problems. By a modified Visick grading system, 91% had a result that was satisfactory or better. This study supports the use of proximal gastric vagotomy as the operation of choice for the elective surgical treatment of duodenal ulcer.

Adult↗
PubMed1983

[Proportion and frequency of 3 kinds of anaerobic bacteria in relation to the gingival index].

The proportion and frequency of three groups of particular bacteria (Bacteroides, Fusobacterium and spirochetes) were studied in relation to the gingival index on the sites from which they were sampled. Seventy eight samples collected from 40 individuals were studied together with measurements of the gingival index and the pocket or sulcus depth. The samples were dispersed by ultrasonic treatment, diluted and cultured on a non-selective medium. The identification of the species was done by biochemical tests and by analysis of the metabolic products with gas chromatography. As a whole, our results support the hypothesis of an important change in the microbial flora from a clinical healthy status (with predominant Gram positive facultative anaerobic bacteria) to disease (with predominant Gram negative strict anaerobic bacteria). Furthermore the results suggest that Bacteroides gingvalis as well as Fusobacterium nucleatum and spirochetes through their high frequency and important proportion at the affected sites played an etiological role in the pathogenesis of gingivitis and periodontis Man.

Adult↗
PubMed1982

Hormonal variations during sleep in men with erectile dysfunction and normal controls.

Five physically healthy young males suffering from erectile impotence and five normal controls of similar age are the subjects of this preliminary report. All were studied in the sleep laboratory during 3 to 5 nights with the last two devoted to sequential hormonal sampling by means of an indwelling venous catheter. Electroencephalogram, eye movements, and penile tumescence were monitored continually through the night. Plasma LH, FSH, and testosterone were measured every 20 minutes by radioimmunoassay. There were no differences between the patients with erectile impotence and normal controls in all sleep parameters investigated, including mean tumescent time, time in simultaneous REM and tumescence, and number of full and partial tumescent episodes. Marked fluctuations in plasma LH, FSH, and testosterone were observed during sleep without differences noted between the two groups. Mean plasma LH, but not FSH or testosterone, was significantly lower in the impotent men. There were no significant differences in mean plasma gonadotrophins and testosterone between tumescent episodes and nontumescent periods in either group. A significant relation was found in normals, but not in the men with erectile dysfunction, between the occurrence of REM sleep and abrupt elevations in testosterone. Testosterone levels during REM sleep with tumescence were also consistently higher than during the condition of non-REM without tumescence in the normal, but not in the impotent, group.

Adult↗
PubMed1982

Pre-hospital analgesia with Entonox.

Pre-hospital self-administered analgesia using a 50:50 mixture of nitrous oxide and oxygen (Entonox) was evaluated in 240 patients. Of these, 93.4 per cent experienced either complete or partial relief from traumatic, chest, abdominal or back pain. Drowsiness was the most common side effect noted. No complications occurred during delivery of the mixture. Attention is drawn to the effect of extreme temperatures on the Entonox mixture and recommendations are made with respect to its use below-freezing climates. Because of its ease of use and short duration of action, Entonox appears to be well suited for the treatment of pre-hospital pain by Emergency Medical Technicians.

Adolescent↗
PubMed1982

Antihypertensive effects of nifedipine combined with cardioselective beta-adrenergic receptor antagonism by atenolol.

The calcium-channel blocker, nifedipine, was used as additional oral therapy to beta-adrenergic receptor blockade by the cardioselective agent, atenolol, in the therapy of 31 patients with hypertension. Initial studies were directed towards control of associated angina pectoris in 15 of the patients, but no effects were found on angina except in two patients. However, arterial blood pressure was consistently reduced in all patients. Further studies on 16 patients were therefore directed towards the use of nifedipine as an antihypertensive agent in addition to atenolol and a thiazide diuretic. Nifedipine (10 mg sublingually) acutely dropped blood pressure by about 30/20 mm Hg (systolic/diastolic) within 20 minutes. Follow-up studies made after 4 to 8 weeks showed that the initial acute response to nifedipine predicted the long-term response to oral nifedipine, 10 mg twice daily. Of 31 hypertensive patients tested, only one failed to respond to nifedipine.

Adrenergic beta-Antagonists↗