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Biomedical subjects

D Weiss

Publications and source records attributed to D Weiss.

At least 145 records · Page 8Linked to original sources

Binding of N-substituted erythromycyclamines to ribosomes.

Several N-substituted erythromycylamines were evaluated for their ability to inhibit the binding of [(14)C]erythromycin to ribosomes. The association and dissociation constants for the binding of each compound to Escherichia coli ribosomes were determined. These studies have resulted in the development of three types of probes for topological studies of the erythromycin-binding site and the ribosome: the chemically reactive bromoacetamido, the photoreactive N-(2)-nitro-4-azidophenyl)glycinamido, and the fluorescent fluorescein isothiocyanate derivatives of 9(S)-erythromycylamine.

Anti-Bacterial Agents↗

Binding of thiostrepton to ribosomes from thiostrepton-sensitive and -resistant Bacillus subtilis strains.

Binding of [(35)S]thiostrepton to ribosomes from thiostrepton-sensitive and -resistant strains of Bacillus subtilis was studied. Ribosomes from thiostrepton-resistant strains bound relatively little thiostrepton compared with ribosomes from thiostrepton-sensitive B. subtilis. In addition, ribosomes from revertant strains that were obtained as thiostrepton-sensitive revertants from thiostrepton-resistant strains bound [(35)S]thiostrepton similarly to ribosomes from the sensitive parental strain.

Anti-Bacterial Agents↗

The sandwich holder.

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Cooking and Eating Utensils↗

Prevention of premature delivery in a unicornuate uterus by cervical cerclage.

A 26-year-old woman had two premature deliveries when 6 months pregnant. Neither produced a living child. A hysterosalpingogram was done, confirming a diagnosis of unicornuate uterus. When the patient became pregnant again, a third and fourth time, cervical cerclage was done in both cases. Pregnancies were terminated by cesarean section because of breech presentation and malformation of the uterus and in each case a healthy living child was delivered. In our view, in order to prevent premature deliveries, when a diagnosis of uterus malformations has been confirmed, a cerclage should be performed.

Adult↗

Lead content of human hair (1871-1971).

Samples of antique and contemporary human hair were analyzed for lead by atomic absorption spectroscopy. Antique hair contained a significantly greater amount of lead than did contemporary hair.

Adult↗