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Biomedical subjects

D Weaver

Publications and source records attributed to D Weaver.

80 records · Page 5Linked to original sources
PubMed1977

A psychogeriatric activity group in a rural community.

Three senior students in occupational therapy and a faculty member collaborated with a community mental health center in implementing and conducting an Outreach Activity Group for socially isolated, psychogeriatric clients residing in an outlying rural community. The students gained experience in five areas: learning the structure, functions, and funding of a community program; identifying the role and function of occupational therapy in community-based mental health; making use of administrative and consultative role functions; leading a group; and, with other health professionals, identifying ways to lessen the problems faced by the psychogeriatric client in the community. The group was helpful in maintaining the psychogeriatric client in the community by promoting self-esteem, self-expression, new interests, constructive use of leisure time, reality testing, interpersonal relationships, and perceptual motor stimulation.

Aged↗
PubMedDate not supplied

Depletion of the predominant B-cell population in immunoglobulin mu heavy-chain transgenic mice.

The transgenic mouse line M54 was generated by introducing a functionally-rearranged immunoglobulin mu heavy-chain gene into the germ line of a C57B1/6 inbred mouse. Previous examination of the antibodies produced by B-cell hybridomas derived from transgenic M54 mice showed that the presence of the mu transgene grossly altered the immunoglobulin repertoire of unimmunized animals, suggesting that these mice suffer from a serious immunoregulatory perturbation. Studies presented here introduce a new perspective on this functional defect. We show that the lymphoid tissues from these transgenic mice lack virtually all conventional bone-marrow-derived B cells, which constitute the predominant B-cell population in normal mice and which typically produce primary and secondary antibody responses to T-cell-dependent antigens. Moreover, the bone marrow from transgenic M54 mice is depleted of pre-B lymphocytes, indicating a serious defect in early B-cell lymphopoiesis. In contrast, CD5 (Ly-1) B cells, a second B-cell population displaying a characteristic set of cell surface markers which are derived from distinct precursors in the peritoneum, are represented at normal frequencies in these transgenic mice. Thus, the presence of the rearranged immunoglobulin heavy-chain transgene in M54 mice results in an unexpected selective developmental defect that impairs the development of bone-marrow-derived pre-B and B cells without affecting Ly-1 B cells.

Animals↗
PubMedDate not supplied

Knowledge workers and knowledge-intense organizations, Part 1: A promising framework for nursing and healthcare.

Although some of the models and practices imported from business and industry have dubious or uncomfortable application to healthcare, one of the rapidly emerging paradigms appears to fit nursing and healthcare well. The concept of the knowledge-intense or knowledge work company or firm, staffed primarily by a workforce of knowledge workers, appears to describe the healthcare organization more accurately than the traditional industrial organization model drawn from the production floor or the sales organization.

Humans↗
PubMedDate not supplied

Summary of well water sampling in California to detect pesticide residues resulting from nonpoint-source applications.

This report summarizes well sampling protocols, data collection procedures, and analytical results for the presence of pesticides in ground water developed by the California Department of Pesticide Regulation (DPR). Specific well sampling protocols were developed to meet regulatory mandates of the Pesticide Contamination Prevention Act (PCPA) of 1986 and to provide further understanding of the agronomic, chemical, and geographic factors that contribute to movement of residues to ground water. The well sampling data have formed the basis for the DPR's regulatory decisions. For example, a sampling protocol, the Four-Section Survey, was developed to determine if reported detections were caused by nonpoint-source agricultural applications, a determination that can initiate formal review and subsequent regulation of a pesticide. Selection of sampling sites, which are primarily rural domestic wells, was initially based on pesticide use and cropping patterns. Recently, soil and depth-to-ground water data have been added to identify areas where a higher frequency of detection is expected. In accordance with the PCPA, the DPR maintains a database for all pesticide well sampling in California with submission required by all state agencies and with invitations for submission extended to all local and federal agencies or other entities. To date, residues for 16 active ingredients and breakdown products have been detected in California ground water as a result of legal agricultural use. Regulations have been adopted for all detected parent active ingredients, and they have been developed regardless of the level of detection.

Agriculture↗
PubMedDate not supplied

An interview with Diana Weaver. Interview by Judith Bachman.

Two Years into her tenure as the vice president for nursing, Yale-New Haven Hospital, Diana Weaver, RN, DNS, is leading a major transformation of patient-care services. She is currently president-elect of the American Organization of Nurse Executives (AONE), a recent inductee to the American Academy of Nursing, a past Johnson & Johnson Wharton Fellow, and a recipient of numerous other significant honors for excellence in both leadership and education. Yale-New Haven Hospital is challenging itself to provide exceptional care to its community while responding to the high demands placed on the industry to expand services and lower costs. As a nursing leader, Ms. Weaver provides the analytical rigor, caring attitude, and great enthusiasm needed to make this project a success.

Hospital Restructuring↗
PubMedDate not supplied

Supporting excellence in turbulent times.

Re-engineering offers an organization the opportunity to identify and strengthen critical system values and enhance employee commitment despite needed downsizing and major role changes. Anticipated distress during turbulent transitions can be decreased by managers paying close attention to employees' realistic concerns and offering opportunities for discussion about unaltered values as well as concretizing operational guideposts during the "in between" phase. Leaders must develop significant new skills to help staff develop competencies related to change management. Chief among the needed capabilities are direct communication techniques, enhanced self knowledge and desired team role behaviors. The expanded span of accountability for managers offers opportunities for staff empowerment through their needed participation in peer reviews, as well as the concomitant changes in position descriptions, role expectations, and financial rewards.

Clinical Competence↗