Search PubMed⌕ Search

Biomedical subjects

D Watkins

Publications and source records attributed to D Watkins.

At least 91 records · Page 5Linked to original sources
PubMed1978

The development and evaluation of self-esteem measuring instruments.

It is argued that a major failing with most existing measures of self-esteem is that they do not even attempt to take into account the value system of the individual subject. A relatively straightforward method of measuring self-esteem was proposed based on an aggregate of a subject's self-ratings in different areas of his life weighted by the relative importance of those life areas to the subject. This approach is used to develop a measure of self-esteem for Australian tertiary students. A self-esteem questionnaire was also developed, based on life areas important to other Australian college students. An evaluation of these two instruments is then reported based on 235 Psychology students at Melbourne University. Some implications of this approach to the structure of self-esteem itself are considered.

Journal Article↗
PubMed1978

An electronic frequency shifting stethoscope for heart sounds.

The predominating energy in the normal heart sounds has been found to be at frequencies below the normal hearing threshold. Because it was felt that significant clinical information was likely to be present at those frequencies, an instrument was designed and fabricated which would frequency shift the entire heart sound into the middle of the auditory frequency range. Clinical testing showed that changes were readily detected in a monitoring situation, and that use of the instrument was both simple and easy to learn.

Anesthesia, Epidural↗
PubMed1976

Effect of alloxan on islet tissue permeability: protection and reversal by dithiols.

The ability of dithiol compounds with different spacing between the thiol (SH) groups to protect against and reversed the action of alloxan on islet tissue permeability, and their ability to inhibit the reaction between alloxan and glutathione (which results in the formation of a compound with a 305 nm absorption maximum) have been examined. Treatment of toadfish islet slices with alloxan markedly increased their permeability to D-mannitol-1-14C, which normally is restricted to the extracellular space. Pretreatment of the slices with 2,3-dimercaptopropanol (BAL) or 1,4-dimercaptobutane (DMB) before treatment with alloxan completely protected them against this action of alloxan, whereas 1,5-dimercaptopentane (DMP) and 1,6-dimercaptohexane (DMH) partially protected and 1,8-dimercapto-octane (DMO) had no effect. When islets were first treated with alloxan and then treated with the dithiols, BAL and DMB reverse the action of alloxan to the greatest extent, DMP was less effective, and DMH had no effect. The effect of the dithiols on the reaction between alloxan and glutathione was consistent with their effects on the alloxan-induced increase in islet permeability; BAL and DMB were the strongest inhibitors, DMP and DMH inhibited to a lesser degree and DMO did not inhibit. These studies support the hypothesis that alloxan damages islet cell membranes by reacting with membrane dithiols formed by two SH groups which are relatively close together.

Alloxan↗