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Biomedical subjects

D Wardell

Publications and source records attributed to D Wardell.

8 recordsLinked to original sources
PubMed1996

An ethnographic assessment of an academic nursing center.

Establishment of nursing centers is one of the most important and most exciting trends in the profession of nursing. Nurse practitioners have been taking the lead in the management and staffing of nursing centers. The purpose of this study was to provide a description and an analysis of an academic nursing center. Through a series of observations and interviews, an interdisciplinary team investigated the history and organizational development of the center; the everyday delivery of services; staffing; and participants' assessment of the efficiency and quality of its services and recommendations for improving the services provided in the examined nursing center.

Anthropology, Cultural↗
PubMed1993

A contemporary view of alternative healing modalities.

Alternative forms of healing have increasingly gained popularity in the United States as evidenced by books, healing groups, and a burgeoning variety of healing modalities. Knowledge about these modalities can facilitate health care providers' effectiveness in managing care by understanding the healing practices selected by patients, and incorporating alternative approaches into holistic case management. A matrix is presented that classifies these modalities according to preparation of the healer and methods of healing. A brief description is provided of various types of alternative healing with some of their potential risks and benefits to health. Suggestions are made regarding selection of a healer and sources of information.

Acupuncture Therapy↗
PubMed1992

A clinical research perspective: look to the obvious.

The solution to nursing problems can often be found by using a combination of a naturalistic approach and traditional scientific methods. To illustrate this link, the development of a pacifier for low birth weight infants is described. The observation of fetus' thumb sucking in utero led to a broadly based literature review that suggested the idea of the thumb as an appropriate model for nonnutritive sucking. An anthropometric study was conducted to determine if the size of the thumb correlated with the size of the mouth. The correlations between the mouth and thumb further strengthened the appropriateness of the thumb as a model for a low birth weight infant pacifier.

Anthropometry↗
PubMed1980

Margaret Sanger: birth control's successful revolutionary.

The year 1979 marked the centennial of Margaret Sanger, birth control pioneer. Sanger worked to secure two new human rights: the right to decide whether to have a child and the right of a child to be wanted. Beginning in 1873, antipornography crusader Anthony Comstock lobbied through Congress and the state legislatures laws forbidding the distribution of contraceptive devices and even information. He equated these with erotic postcards as "obscene, lewd, lascivious, filthy, indecent and disgusting." Sanger's strategy was to challenge the Comstock laws in the courts. She studied birth control methods abroad and published a pamphlet, Family Limitation, in 1914. It was the first modern marriage manual; it was also illegal. The publicity her trial generated was immense and highly sympathetic. The government dropped its case when it saw it could only make her a martyr. An obstetrical nurse, Sanger had seen the plight of factory women in the poorest sections of New York City. In order to provide the medical advice and supplies women clamored for, Sanger opened the first U.S. birth control clinic, in Brooklyn in 1916. The New York City Vice Squad raided and closed it, and jailed Sanger. Margaret Sanger underwent other trials, raids, and harassments, but each time won additional public support for her organization--Planned Parenthood--and her cause.

Contraception↗
PubMed1979

Programmed appearance of translatable flagellar tubulin mRNA during cell differentiation in Naegleria.

The programmed de novo synthesis of flagellar tubulin during the hour-long differentiation of Naegleria gruberi from amoebae to flagellates is our paradigm for the study of gene expression during cell differentiation. This paper reports the efficient translation of flagellar tubulin mRNA in the wheat germ cell-free system directed by total or polyadenylated RNA extracted from differentiating cells. The tubulin in the in vitro product has a subunit molecular weight of 55,000, separates into alpha and beta subunits under suitable conditions of polyacrylamide gel electrophoreis and co-polymerizes with calf brain tubulin. At least half of the tubulin synthesized in vitro is precipitated by antibodies specific to flagellar tubulin, and the immunoprecipitated tubulin subunits yield peptide maps similar to those of outer doublet tublin. Flagellar tubulin is the predominant protein synthesized in the cell-free system, and amounts to about 5% of the polypeptides whose synthesis is directed by total RNA from differentiating cells. In contrast, little or no flagellar tubulin is synthesized when the cell-free system is directed by RNA extracted from amoebae prior to differentiation. Translation assays show that at least 92% of the flagellar tubulin mRNA appears during differentiation. The time course of appearance of this mRNA was measured by quantitative immunoprecipitation of the cell-free products. Under conditions where cells from flagella 60 min after initiation of differentiation, translatable flagellar tubulin mRNA was first detected at 20 min, reached a maximum at about 60 min and then declined. An excellent correlation was observed between the amount of translatable flagellar tubulin mRNA and the previously measured rates of flagellar tubulin synthesis in vivo. These results indicate that synthesis of flagellar tubulin is a direct reflection of the abundance of its mRNA, and provide the molecular techniques for dissection of the factors that regulate the rapid appearance of this structural protein during differentiation.

Animals↗