Studies on human gastric gel mucin. Isolation and characterization of a major glycoprotein component.
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Amino Acids↗
Biomedical subjects
D Waldron-Edward
Publications and source records attributed to D Waldron-Edward.
Studies on the inhibition of intestinal absorption of radioactive strontium. 8. The effect of alginate-containing diets on water metabolism.
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Agar↗
Studies on inhibition of intestinal absorption of radioactive strontium. VII. Relationship of biological activity to chemical composition of alginates obtained from North American seaweeds.
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Alginates↗
Studies on the inhibition of intestinal absoprtion of radioactive strontium. VI. Alginate degradation products as potent in vivo sequestering agents of radioactive strontium.
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Alginates↗
Physicochemical properties of gastric mucus and its role in the pathogenesis of gastric lesions.
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Amides↗
Studies on the inhibition of intestinal absorption of radioactive strontium. V. The effect of administration of calcium alginate.
A method of selective suppression of absorption of radioactive strontium from ingested food material is described which allows calcium to be available to the body. In the present study the effects of administering calcium alginate were determined. Studies on the relative binding of Ca and Sr by calcium alginate in vivo are also important to the investigation of calcium-strontium exchange.Samples of calcium alginate were obtained commercially or prepared from sodium salts and the binding properties with Ca(45) and Sr(89) were tested in vivo. There was a free exchange of radioactive calcium as well as of strontium with bound inactive calcium. The amount of Ca(45) retained in the gut by calcium alginate is proportionally less than Sr(89), so that the ratio Sr(89)/Ca(45) in the bone is consistently and significantly lower in treated rats. Calcium alginate acts differently from other calcium salts, although in a manner similar to sodium alginate.
Alginates↗
Mobilities of amino acids and peptides in paper electrophoresis.
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Amino Acids↗
Effects of the counter ion and pH on intestinal absorption of calcium and strontium.
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Animals↗
Suppression of intestinal absorption of radioactive strontium by naturally occurring non-absorbable polyelectrolytes.
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Alginates↗
The micro determination of acid and base dissociation constants by paper electrophoresis.
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Acids↗
Calculation of relative zone mobilities in paper electrophoresis.
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Amines↗
In vitro action of gastric mucosal lysosomal enzymes on intracellular gastric glycoproteins.
The results show that incubation of gastric mucosal cells from rat at pH approximately 4.5 or in the presence of aspirin is associated with a specific increase in the activity of some acid-hydrolases. Intracellular glycoproteins, isolated by non-degrative techniques from rat or dog fundic mucosal cells, were found to be potential bio-substrates for these acid-hydrolyses. This may suggest that cleavage of the carbohydrate moieties of the intracellular and mucosal cell wall glycoproteins is a fundamental step in the development of gastric ulceration. A model for gastric lesions is proposed and discussed in the light of the results obtained.
Animals↗