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Biomedical subjects

D W Pilling

Publications and source records attributed to D W Pilling.

29 records · Page 2Linked to original sources
PubMed1983

Infantile hypertrophic pyloric stenosis: a fresh approach to the diagnosis.

Infantile hypertrophic pyloric stenosis is a condition occurring in early infancy. The traditional approach to the diagnosis has been clinical, relying on the palpation of a 'tumour' caused by the muscular thickening of the pylorus. In doubtful cases a barium meal is diagnostic. Ultrasound, with the lack of hazards associated with radiation, provides an additional method of investigation which is accurate and will diagnose some cases in which no pyloric tumour is palpable. This will spare infants from a barium meal but there are still cases in which a barium meal will be necessary because a tumour cannot be palpated or demonstrated by ultrasound.

Barium Sulfate↗
PubMed1981

The radiology of Meconium Ileus Equivalent.

Meconium Ileus Equivalent is a condition which occurs in patients with cystic fibrosis where the ileum becomes obstructed by bowel content of abnormal consistency. Intercurrent chest infection or absence of pancreatic extract supplements are often the exacerbating cause. Plain films of the abdomen show small bowel obstruction and in some a nodular pattern in the small bowel, the nodules being larger than those seen in quiescent cystic fibrosis. Gastrografin enemas and/or enemas with acetyl cysteine can be used in the treatment of the condition, the Gastrografin having the advantage of confirming the diagnosis radiologically. The condition is important as it can be the presenting feature of cystic fibrosis in childhood and even in early adult life, and the operative mortality and morbidity are high. Conservative treatment should be pursued vigorously and operation only undertaken if unavoidable.

Child↗
PubMed1978

Radiological abnormalities associated with anomalies of the ninth chromosome.

The clinical and radiological features of Trisomy of the short arm of the ninth chromosome and of the Nail Patella Syndrome, both of which conditions are related to abnormalities of the ninth chromosome, are compared. Dislocation of the head of radius is seen in both conditions, as is a diminished patello condylar ratio. Several of the features described as being sporadic anomalies in the Nail Patella Syndrome are also seen in some patients with Trisomy of the Ninth Chromosome. The Trisomy 9 group also have several anomalies which are shared with Trisomy 21, Trisomy 17/18, Trisomy 13/15 and Trisomy 4, suggesting that some of these changes are a non-specific result of chromosome abnormality rather than being specific to the Trisomy 9.

Chromosome Aberrations↗
PubMedDate not supplied

Persistent acquired lobar overinflation complicating bronchopulmonary dysplasia.

UNLABELLED: Persistent acquired lobar overinflation (PALO) may complicate bronchopulmonary dysplasia (BPD). From infants admitted to the regional neonatal intensive care unit or who had been followed up at the chronic lung disease clinic in Liverpool over a 6.5-year period, 11 children with BPD and PALO were identified and details of their neonatal and subsequent outcome obtained. Their median gestational age was 29 weeks (range 24-33) and median birth weight was 1317 g (range 676-1968 g). All had received ventilatory support for severe neonatal respiratory distress syndrome for a median of 26 days (range 5-86). The median age the acquired lobar overinflation was detected was 82 days (range 45424 days). Nine patients required continued neonatal or paediatric intensive care re-admission for deteriorating respiratory function. Six children have subsequently died at a median age of 9.5 months (range 6.5-20). Five patients underwent bronchoscopy, four suggesting the presence of bronchomalacia. Three patients had ventilation-perfusion scans all showing that the overinflated lobe had no mismatch defect unlike other areas of the lung. CONCLUSION: The place of specific therapies for persistent acquired lobar overinflation is unclear. Surgery to remove the overinflated lobe in such cases may be inappropriate and the outcome of this complication of bronchopulmonary dysplasia appears to be poor.

Bronchopulmonary Dysplasia↗
PubMedDate not supplied

Ovarian ultrasound.

Ovarian ultrasound is applicable to all ages, from the fetus through childhood and adolescence to the premenopausal and finally postmenopausal women. Indications include the chance finding of an ovarian lesion in the fetus, the diagnosis of ovarian pathology resulting in symptoms and the uses of follicle monitoring in infertility and screening for ovarian cancer in high-risk groups.

Adolescent↗