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Biomedical subjects

D W Bethune

Publications and source records attributed to D W Bethune.

At least 37 records · Page 2Linked to original sources

A comparison of five heat and moisture exchangers.

Five heat and moisture exchangers were investigated to compare their efficiency of humidification, their ability to filter bacterial spores and their various physical properties. The results are presented and the various mechanisms of heat and moisture exchange are reviewed. The Pall Ultipor BB50, because of its hydrophobic properties, has a slightly different action from heat and moisture exchangers already in use, The place of the Pall Ultipor BB50 in clinical practice is discussed.

Filtration↗

Haemodialysis and haemofiltration on cardiopulmonary bypass.

Over a three year period we have used haemodialysis and haemofiltration in parallel with cardiopulmonary bypass in 26 patients. Impaired renal function and excessive fluid retention have been the main indications. Patients on haemodialysis programmes for end stage renal failure did not require further dialysis until at least the third postoperative day, when they could tolerate the haemodynamic disturbance of dialysis. In the other patients these techniques proved valuable in reversing the effects of haemodilution and in controlling the concentration of serum potassium. Our experience has confirmed that haemodialysis and haemofiltration in parallel with cardiopulmonary bypass are useful adjuncts in the perioperative management of patients with impaired renal function undergoing open heart surgery. The techniques are also effective in correcting the fluid retention and biochemical imbalance in patients with congestive cardiac failure, including those with heart transplants.

Adolescent↗

Use of partial cardiopulmonary bypass during the anhepatic phase of orthotopic liver grafting.

Femoro-femoral partial cardiopulmonary bypass has been used in two patients under going orthotopic liver allografting who had severe cardiovascular disturbances on trial clamping of their venae cavae. Flows of 2-3 litres/min resulted in satisfactory cardiovascular control during the anhepatic phase in each ase. A third patient who tolerated caval clamping withstood the grafting without bypass. Having bypass available for use in critical cases could increase the safety of orthotopic liver transplantation.

Adult↗

Day case anaesthesia and memory.

Two simple anaesthetic techniques were administered to forty healthy women undergoing minor gynaecological surgery. There was a significantly shorter immediate recovery period following the use of a fentanyl and methohexitone technique. Memory function testing revealed an impairment of the ability to retain new information following anaesthesia. This returned to normal within 3 hr.

Adult↗