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Biomedical subjects

D Vidyasagar

Publications and source records attributed to D Vidyasagar.

189 records · Page 11Linked to original sources
PubMedDate not supplied

Immediate and long-term outcome of infants less than 1000 grams.

In order to assess the immediate and long-term outcome of very low birth weight infants, a retrospective analysis of clinical and biochemical parameters of 100 consecutive newborns with birth weights less than 1000 g was carried out. Overall neonatal mortality for this group was 69%. For infants between 751 to 1000 g, the mortality rate was 52%. Of the 23 infants who were discharged, neurodevelopmental assessment was performed in 16. Twelve of the 16 were neurologically normal. The data indicate a favorable prognosis for infants with birth weight less than 1000 g.

Follow-Up Studies↗
PubMedDate not supplied

The oral effects of orotracheal intubation in prematurely born preschoolers.

This cross-sectional study of fifty-two prematurely-born children, ages two to five years, evaluated the long-term effects of oral intubation at birth on palatal architecture, crossbite malocclusion, and enamel structure. Seventy percent showed a high palatal vault, with palatal grooving in 25 percent; 36 percent had enamel defects in the maxillary primary incisors; and 17 percent had posterior crossbites. The mean palatal depth was 12.9 mm, as compared to 11.4 mm for a group of 45 nonintubated, normal healthy children (the difference was significant at alpha = 0.05). There are significant iatrogenic defects from prolonged neonatal intubation with this sample of preschoolers.

Child, Preschool↗
PubMedDate not supplied

Intraoral prosthetic appliance for the prevention of palatal grooving in premature intubated infants.

Palatal groove is one of the complications of orotracheal intubation in premature infants. Previous reports demonstrated an incidence of 48% of palatal groove formation in premature infants which increased to 88% when the duration of intubation was greater than two weeks. A prosthetic intraoral acrylic appliance which has successfully prevented such a groove formation has been described in this paper.

Humans↗
PubMedDate not supplied

Serum indirect bilirubin levels and meconium passage in early fed normal newborns.

The purpose of this study was to investigate the effect of early feeding of the normal newborn with formula and sterile water on: time of initial meconium passage, serum indirect bilirubin levels at 48 hours of life (HOL), observed jaundice at 48 HOL, and percentage of weight change at 48 HOL. Thirty normal, term newborns were sequentially assigned to one of three treatment groups: a control group given the routine hospital feeding of up to 30 ml of sterile water at 4 HOL and up to 30 ml of formula at 8 HOL; a water-fed group given up to 30 ml of sterile water at each feeding at 1, 2, and 3 HOL; and a third group fed formula at the same times and in the same amounts as the water-fed group. The time of initial meconium passage was significantly earlier in both groups of early fed infants than in the control group, F = 4.202, p = .026. The difference between the water-fed and the formula-fed groups was not statistically significant, but the mean time of passage was earlier in formula-fed infants. Serum indirect bilirubin levels at 48 HOL did not differ significantly, F = 0.412, p = .666, although the mean for the formula-fed group was lower. The correlation between the time of initial meconium passage and serum indirect bilirubin levels at 48 HOL was r = .3271, p = .083. Nine infants in the control group were jaundiced, compared to six in the water-fed group and six in the formula-fed group, a difference that was statistically significant, chi 2 = 6.79, p = .034.(ABSTRACT TRUNCATED AT 250 WORDS)

Adolescent↗