Search PubMed⌕ Search

Biomedical subjects

D Verhulst

Publications and source records attributed to D Verhulst.

8 recordsLinked to original sources
PubMed1998

Vocal cord immobilisation in diffuse idiopathic skeletal hyperostosis (DISH).

Advanced forms of diffuse idiopathic skeletal hyperostosis or Forestier's disease can induce dysphagia and significant respiratory symptoms such as hoarseness, dyspnea, snoring and laryngeal stridor. Severe respiratory distress is very rare. Two identical cases of chronic respiratory distress due to bilateral vocal cord adduction-fixation in conjunction with skeletal pathology in the cervical area are presented. The clinical, diagnostic and therapeutic work-up and the prognostic outcome of the laryngeal pathology are discussed.

Aged↗
PubMed1988

Physical and psychological symptoms experienced by Canadian women and their husbands during pregnancy and the postpartum.

This study was designed to determine the type and frequency of physical and psychological symptoms reported by pregnant and postpartal women and their husbands, and to determine the relationship between spouses' strength of identification and similarities in their reports of symptoms. The sample included 20 couples who resided in south-eastern Ontario, Canada who completed a checklist of 20 physical and three psychological symptoms. Findings indicated that wives and husbands experienced a variety of physical and psychological symptoms during pregnancy and the postpartum. Although few symptoms were shared by spouses, the similarities in their reports were statistically significant. There was no evidence of a relationship between spouses' strength of identification and similarities in their symptom reports.

Adult↗
PubMed1988

Pancreatic function after seromyotomy of the canine stomach.

Anterior gastric seromyotomy combined with posterior truncal vagotomy has been proposed as an acid-reducing operation for patients with duodenal ulcer. Section of the posterior vagal trunk could, however, be held responsible for reduced pancreatic function, seen in patients after bilateral truncal vagotomy. In this study the pancreatic function after anterior gastric seromyotomy and posterior truncal vagotomy has been evaluated in a series of canine experiments by means of a direct hormone stimulation test. No reduction of the basal or stimulated exocrine pancreatic secretion was noted after this type of vagotomy.

Amylases↗
PubMed1983

Enzyme kinetics: a new procedure for data normalization.

A procedure is proposed to normalize enzymatic reaction velocities measured in separate experiments. After calculation of the Km and maximum velocity in each individual set of data, the velocities measured in each experiment are reanalyzed by regression analysis with the constraint that they yield a Km identical to the geometric mean of the individual Km's calculated originally. The V derived from this second analysis can be taken, in each experiment, as the reference value relative to which all reaction velocities are normalized. All normalized velocities are eventually pooled together to establish the final regression line. This relatively simple and reliable procedure overcomes several difficulties otherwise encountered when the kinetics of an enzymatic reaction are judged from data collected in separate experiments.

Enzymes↗
PubMed1982

Mathematical modelling of cyclic AMP-Ca2+ interactions in pancreatic islets.

A mathematical model is proposed to account for the interactions between Ca2+ and cyclic AMP in the process of glucose-induced insulin release. This model allows simulation of experimental findings such as the glucose-induced accumulation of cyclic AMP in islet cells, the calcium dependency of the latter accumulation, the time course of 45Ca net uptake by the islets exposed to glucose and/or a phosphodiesterase inhibitor, the stimulation of insulin release by glucose, the suppression of such a release at low extracellular Ca2+ concentration and its amplification by phosphodiesterase inhibitors, the restoration of a significant secretory response to glucose in islets deprived of Ca2+ but exposed to a phosphodiesterase inhibitor, and the usual relationship between 45Ca net uptake and insulin release. All these data refer to studies performed over a 90-min incubation. The model is not suitable, however, to simulate the rapid response of the islet cells during the first few minutes that follow a change in the environment of the islets.

1-Methyl-3-isobutylxanthine↗
PubMedDate not supplied

[Lasers and E.N.T].

Explore the source record for details and available documents.

Adult↗
PubMedDate not supplied

High-dose cytotoxic therapy with autologous bone marrow or peripheral blood progenitor cell transplantation in malignant lymphomas.

The present paper is an attempt to assess the efficiency of high-dose cytotoxic therapy followed by autologous bone marrow or peripheral progenitor cell rescue with hematopoietic growth factor support given in a group of 27 patients (16 men, 11 women) at the Department of Hematology of the Mont Godinne University Clinics, mainly in the same interval 1990-1994. The reasons for introducing such a therapy in these patients (6 with Hodgkin's disease, 14 with intermediate or high grade, aggressive non Hodgkin lymphomas and 7 with low grade follicular non Hodgkin lymphomas) were relapse of disease after conventional therapy (11 cases), resistance to initial therapy (5 patients) or because of histologically proven transformation to a more aggressive form (one case); in 10 patients with extended, poor prognosis forms, the procedure was used as part of the first line therapy. The conditioning high dose chemotherapy was given according to various regimens, most of them containing Cyclophosphamide, BCNU and Etoposide, with or without total body irradiation. In 14 patients, bone marrow (BM) graft was used, while peripheral blood progenitor cells (PBPC) were infused in the remaining 13 patients. The number of infused granulocyte-macrophage colony forming units (CFU-GM) ranged between 7,650 and 3,900,000/kg, with a mean value of 461,000/kg. The median time intervals required to reach an absolute neutrophil count > 500/microliter, a platelet count > 50,000/microliter and a hematocrit > 30% were 13 days, 20 days and 23 days respectively. Growth factors (GM-CSF and G-CSF) and PBPC use shortened the time for neutrophil recovery as well as neutropenia-related complications. No procedure-related death was observed and complete remission was achieved in 22 cases (81.4%); after a mean follow-up of 32.6 months, 14 patients (55.5%) are alive and free of disease, while in 7 patients (31% of the complete responders) relapse occurred at an average time interval of 8.2 months since the procedure.

Adult↗