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Biomedical subjects

D V Dado

Publications and source records attributed to D V Dado.

25 records · Page 2Linked to original sources

Radiographic analysis of the midface of a stillborn infant with a unilateral cleft lip and palate.

The midface of a full-term stillborn infant with a right complete unilateral cleft lip and palate was studied with plain-film radiography and tomography, xeroradiography, and computerized axial tomography. Gross skeletal and soft-tissue deficiencies on the cleft side were evident as compared to the noncleft side and involved the entire bony maxillary complex and antrum, the orbit, and the nasal pyramid and intranasal structures. The area on the cleft side was 19 percent less than the noncleft side, and the maximal anteroposterior dimension was 16 percent less. The cleft bony palatal shelf was 12.5 mm wide compared to 20 mm on the noncleft side. The findings demonstrate the deficient and abnormal functional matrix inherent in the cleft condition.

Cleft Lip↗

Anatomy of the orbicularis oris muscle in incomplete unilateral cleft lip based on histological examination.

Histological sections of tissue removed from three incomplete cleft lips at the time of repair, a nature's scar line, and a noncleft lip were examined serially in the horizontal and saggital planes. The findings confirm previous data from electrical stimulation studies of clefts and a three-dimensional histological model of the orbicularis oris in a complete cleft lip. There is a disorganized mass of muscle fibers with numerous dermal insertions and no evidence of well-defined muscle bundles running parallel to the cleft margins. The fibers are somewhat hypoplastic and less abundant than those present in noncleft lips.

Child↗

Upper and lower lip reconstruction using the step technique.

The step technique for lip reconstruction is a simple, flexible, one-stage operation that allows reconstruction of full-thickness defects spanning up to two-thirds of the lower lip and, in our experience, one-half of the upper lip without violating the opposite lip or using distant advancement flaps. Twelve patients, ranging in age from 24 to 86 years, underwent full-thickness lip excisions for squamous cell and deeply invading basal cell carcinomas. Reconstruction was achieved by advancing the remaining lateral lip elements to close the defects in a stepwise fashion without violating the remaining orbicularis oris muscle. All patients had a symmetrical, mobile, oral sphincter with intact commissures, adequate buccal sulcus, no symptomatic microstomia, and normal sensation at the completion of the procedure. There have been no recurrences in a nine-month to four-year follow-up, and satisfactory aesthetic results were achieved.

Adult↗

The anatomy of the orbicularis oris muscle in unilateral cleft lip based on a three-dimensional histologic reconstruction.

The midface of a full-term, stillborn infant with a right complete unilateral cleft lip and palate has been examined by serial histologic sections and a three-dimensional model has been created. The arrangement of the orbicularis oris muscle fibers observed differs markedly from previous descriptions. There is a chaotic arrangement of muscle fibers with no separate muscle layers distinguishable. Muscle fibers on both sides of the cleft insert into the dermis, although the amount of muscle on the medial side is quite sparse compared with the lateral side. There is no evidence of muscle bundles paralleling the cleft margins. An unexpected finding is a significant number of muscle fibers streaming over the cleft ala. In view of these findings, differing as they do from previous reports, there would seem to be strong justification for histologic investigation of the arrangement of muscle fibers in cleft lip to be repeated as further specimens become available.

Angiography↗