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Biomedical subjects

D Uttley

Publications and source records attributed to D Uttley.

65 records · Page 4Linked to original sources

Subjective impairment and social recovery after closed head injury.

The level of social recovery achieved by a representative series of 50 young adults was assessed six months after a severe closed head injury (post-traumatic amnesia greater than 24 hours). Work, leisure activities, and contact with friends were the areas of life most affected, whereas family life and marital relationships appeared to withstand changes at this stage in the recovery process. Many patients were still suffering from subjective symptoms, but these appeared to have relatively minor effects on ability to resume normal activities. Physical disability was a much more important factor at this stage. A control group of patients with limb injuries suffered similar disruption of their lives, but reported few subjective complaints.

Adolescent↗

Stresses upon the relatives of head-injured patients.

As part of a prospective study of closed head injury, 54 relatives were interviewed within a month of the patient's accident and again six and twelve months later. The degree of stress on the relatives was measured by means of the Wakefield Depression Scale and by interview questions. The worst period of stress for the majority of relatives appeared to be during the first month after the accident. However, the degree of stress appeared to level off by the sixth month and no further diminution was found at twelve months. Stress was apparently mediated by the relatives' perception of personality changes and subjective defects. It was not affected by the severity of the head injury or associated disabilities, nor by whether the patient had resumed work and leisure activities. The nature of the stress is analysed and methods of alleviating it discussed.

Craniocerebral Trauma↗

E.M.I. scan in the management of head injuries.

The E.M.I. scan has much simplified the management of head injuries. The conventional investigations have been supplanted by a safe non-invasive technique, in which lesions of the brain can be demonstrated. Thus high density intracerebral or extracerebral haematoses are readily diagnosed, even when they are in unusual sites. Wherever their location, they appear in sharp contrast to the low density of cerebral contusions or chronic subdural haematomas. The safety of the procedure recommends its sequential use in patients who fail to improve or who deteriorate; and repeated examinations can be useful in monitoring the response to therapy. Under clinical supervision, the quantity and quality of information the method yields during a single comprehensive study is such that it should became the definitive investigation in the victims of cerebral trauma.

Angiography↗

The analysis of radioisotope brain scans by comparison with normal patterns of uptake.

A previously described method for the computer analysis of radioisotope brain scans has been further developed. A patient scan is matched with a series of "normal" scans to find the closest fit and the "normal" scan is then subtracted from the patient scan. The results are displayed in terms of the standard deviation from the normal. In a clinical trial the computer assessments were found to be less accurate than those of two groups of observers. One reason for these disappointing results is related to the simple criteria used to choose and fit the best "normal" to a particular patient scan. A second reason is the optimization of the scanner/photoscan combination to 99Tcm pertechnetate as a brain scanning agent which results in patient-to-patient variation becoming more important. This reduces the potential of a simple numerical analysis to improve results.

Brain Diseases↗

Benign aqueduct stenosis in adults.

A series of 55 cases is described in which hydrocephalus associated with non-neoplastic narrowing of the Sylvian aqueduct produced symptoms for the first time in adult life. The clinical features of the patients and their investigation are described and discussed.

Adolescent↗