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Biomedical subjects

D Upson

Publications and source records attributed to D Upson.

7 recordsLinked to original sources

Recruiting adolescents into qualitative tobacco research studies: experiences and lessons learned.

An increasing barrier to the development and implementation of effective youth smoking prevention and cessation programs involves recruiting adolescents into research studies. Even for non-intervention studies, issues of consent, confidentiality, and motivation to participate are important considerations. In 1996, 11 Prevention Research Center sites across the country conducted qualitative research using focus groups to explore ethnic differences in smoking among adolescents. The diversity in strategies used to interest, motivate, and retain potential focus group subjects provided a rich data set for information about effective strategies and challenges to recruitment. This article presents an overview of recruitment methods used in a multi-site qualitative study on adolescent tobacco use, reports on successful and less successful strategies, and provides recommendations for future recruitment.

Adolescent

AVMA guidelines on compounding.

Relative to a compounded product, the following are responsibilities of the veterinarian. I. They must be able to prepare the product and have knowledge of all ingredients. II. They must be responsible for the safety of the product to the target animal, and that there are no violative residues. III. The product must have efficacy for the intended indications. IV. The veterinarian must establish need for the product to improve the health and/or welfare of the animals. This, therefore, involves: jurisprudence; responsibility to the animals and their owners; and responsibility to society. A common sense approach to this discussion would simply be that if one is not totally comfortable and satisfied medically and pharmacologically with any treatment, including compounded medications, do not use it. This also follows and is based on proper diagnosis, need for treatment, objectives of the treatment, and setting up the regimen. This is as Hippocrates admonished us, "above all, do no harm."

Animals

Branched chains support postoperative protein synthesis.

A blinded, prospective trial of the effects of branched-chain amino acid (BcAA)-enriched total parenteral nutrition (TPN) versus standard TPN was undertaken in nonseptic noncirrhotic abdominal surgery patients and patients with multiple traumatic injuries. The study reflected data from the immediate 7-day postoperative period. With isocaloric and isonitrogenous input, the BcAA-TPN patients achieved positive nitrogen balance on day 3. Although the urinary nitrogen output was decreased by day 3 in BcAA-TPN, the plasma BcAA levels did not increase until day 6. With no change in 3-methylhistidine urinary excretion, the early nitrogen retention with BcAA-TPN probably reflects a stimulation of protein synthesis. The ability to favorably modulate the metabolic stress response with alternate fuels has become a clinical reality.

Adult