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Biomedical subjects

D Turck

Publications and source records attributed to D Turck.

At least 163 records · Page 9Linked to original sources
PubMed1988

[Dumping syndrome: a case after Nissen's operation].

We report on a case of dumping syndrome 1 month after Nissen fundoplication in a 5 month-old infant presenting with symptoms of late hypoglycemia. Blood glucose levels in pre- and post-prandial periods, oral glucose tolerance test and isotopic gastric emptying study confirmed the diagnosis. All symptoms resolved with diet therapy which could be stopped 8 months later. Dumping syndrome is not a so rare complication of gastric surgery and should be considered in patients with non specific symptoms.

Dumping Syndrome↗
PubMed1988

[Ring chromosome 9. Case report and review of the literature].

We report on a girl with ring chromosome 9, and review the 9 other cases of the literature. The main signs of this de novo chromosomal anomaly are: severe microcephaly, growth and psychomotor retardations, and heart malformations. Infectious complications occurs often. We found a decreased level of leucocyte interferon.

Abnormalities, Multiple↗
PubMed1988

[Intestinal biopsy: fiberscopy or Watson's capsule?].

We compared the results of 100 fiberendoscopic small bowel biopsies (F) with those of 100 Watson capsule biopsies (W). Three to 6 specimens were obtained during endoscopy. The F biopsy fragments were deeper than the W biopsies (P less than 0.001). The F biopsies were more often located in the duodenum than the W biopsies. The failure rate of the F biopsies (3%) was lower than for the W biopsies (12%): P less than 0.02. Multiple biopsies increased the diagnostic value of fiberendoscopy, which was 85% in our experience versus 77% for Watson capsule. The duration of the endoscopic procedure, available in 15 children, was 6.5 min for 4 to 6 samples, i.e. 1.5 min by specimen. Small bowel fiberendoscopy appears to be a safe and accurate method for performing small bowel biopsies in infants and children.

Adolescent↗
PubMed1987

[Pancreatic injuries in children. Apropos of 22 cases].

22 cases of blunt pancreatic trauma are reported (17 boys, 5 girls) for the period 1968-1986; 5 of them were received later after the accident. Early diagnosis was not made in eight polytrauma and suspected in 9 abdominal trauma; CT scanner confirmed it at earlier period (1 case); the lesion was revealed later by complication (pseudo-cyst) in 5 cases. The operative treatment (20 times for 22 children) included 15 earlier laparotomies, 1 secondary laparotomy (drain 8, suture 3, partial pancreatectomy 3, duodeno-pancreatectomy 1). 5 late interventions were performed for pseudo-cysts (4 parietal drain; 1 Roux-internal derivation). The results comprise 1 death, 7 good results and 14 cases with different complications but secondary available results.

Child, Preschool↗
PubMed1986

[Laparoschisis: therapeutic problems. Apropos of 48 cases].

A non-selective series of 48 neo-nates was treated during a period of 8 years (1978-1985), with follow-up more than four months for recent observations. Surgical treatment comported Gross-technique in 32 cases; immediate total-closure in 7 cases and progressive reintegration (Schuster) in 10 cases. Long-term parenteral nutrition was performed in 38 neo-nates. The etiology of different deaths (toxic++-infection, mechanical obstruction) is discussed. The percentage of survivors was progressively raised: 70% since 3 years, and better in the last 11 cases, all with good result.

Abdominal Muscles↗
PubMedDate not supplied

Intestinal permeability to [51Cr]EDTA in children with Crohn's disease and celiac disease.

[51Cr]EDTA was used as a probe molecule to assess intestinal permeability in 7 healthy control adults, 11 control children, 17 children with Crohn's disease, and 6 children with untreated celiac disease. After subjects fasted overnight, 75 kBq/kg (= 2 microCi/kg) 51Cr-labeled EDTA was given by mouth; 24-h urinary excretion of [51 Cr]EDTA was measured and expressed as a percentage of the total oral dose. Mean and SD were as follows: control adults 1.47 +/- 0.62, control children 1.59 +/- 0.55, and patients with Crohn's disease or celiac disease 5.35 +/- 1.94. The difference between control children and patients was statistically significant (p less than 0.001). These results show that intestinal permeability to [51Cr]EDTA is increased among children with active or inactive Crohn's disease affecting small bowel only or small bowel and colon, and with untreated celiac disease. The [51Cr]EDTA permeability test could facilitate the decision to perform more extensive investigations in children suspected of small bowel disease who have atypical or poor clinical and biological symptomatology.

Administration, Oral↗
PubMedDate not supplied

Local antibiotic lock for the treatment of infections related to central catheters in parenteral nutrition in children.

BACKGROUND: Central venous catheter-related (CVC) infections represent the most common complication of parenteral nutrition. These infections are usually treated by means of long-term systemic antibiotic treatment. The objective of this study was to determine the efficacy of combining a local antibiotic lock with a short systemic double antibiotic to treat CVC-related staphylococci infections. METHODS: Any child with coagulase-negative staphylococci or Staphylococcus aureus septicemia, confirmed by a positive blood culture, was included in the study. A double antibiotic systemic treatment composed of amikacin and teicoplanin was started and continued for 5 days. The antibiotic treatment was combined from the first day (D0) with a local teicoplanin lock, which was left for 12 hours a day in the catheter for 15 days. Parenteral nutrition was continued on a nocturnal cyclic mode during antibiotic treatment. The efficacy of the treatment was evaluated by clinical (body temperature), biologic [C-reactive protein levels (CRP)], and bacteriologic (blood culture) measures. RESULTS: Twenty CVC-related infection episodes in 13 patients were analyzed for the study. In the initial biologic test, CRP varied from 2 to 130 mg/L (mean 43 mg/L). After 3 days of treatment, CRP varied from 2 to 61 mg/L (mean 12 mg/L). The median time until normalization of temperature and CRP levels after the beginning of antibiotic treatment was 3.2 days (range 1 to 14 days) and 6.2 days (range 2 to 19 days), respectively. All blood cultures were negative for infection 48 hours after stopping the treatment. Only 1 therapeutic failure was observed during the treatment. The patient had persistent signs of clinical septicemia that required removal of the CVC. Two catheter-related infection recurrences were observed in the month after termination of the local antibiotic lock, which also required removal of the CVC. The central venous catheter was maintained in the other cases. CONCLUSIONS: Teicoplanin antibiotic locks, combined with a short conventional systemic antibiotic treatment and continuation of cyclic parenteral nutrition, seem effective and well-tolerated treatments for CVC infections.

Adolescent↗
PubMedDate not supplied

[Abnormalities of intestinal permeability of 51Cr-EDTA in mucoviscidosis].

Intestinal permeability to 51Cr-EDTA was studied in 20 children with cystic fibrosis (CF) and a mean age of 10.7 years, in 7 control adults and in 11 control children. 51Cr-EDTA urinary excretion (mean +/- SD) expressed as a percentage of the orally administered activity was: control children: 1.59 +/- 0.55%, control adults: 1.47 +/- 0.62%, CF patients: 10.7 +/- 8.6%. The difference between CF patients and control children on one hand, between CF patients and control adults on the other hand, was statistically significant (p less than 0.001). Only 3 CF patients had values within the limits of those observed in controls. A statistically significant correlation (p less than 0.01) was observed between the 51Cr-EDTA urinary excretion and steatorrhea. No correlation was found between 51Cr-EDTA urinary excretion and the following parameters: age, sex, weight, height, Shwachman score, liver cirrhosis, oral administration of a mucolytic agent. The eventual, especially nutritional, consequences of this increase of the intestinal permeability in the course of CF remain to be clarified.

Adolescent↗