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Biomedical subjects

D Teculescu

Publications and source records attributed to D Teculescu.

120 records · Page 7Linked to original sources

Respiratory input and transfer impedances in children 9-13 years old.

Reference values for respiratory impedances in children are scarce and limited to the situation where pressure is varied at the mouth. Total respiratory impedance was therefore measured from 4 to 30 Hz in 69 healthy children (9-13 yr) with both a pressure input at the mouth (input impedance, Zin) and a pressure input at the chest (transfer impedance, Ztr). Zin was characterized by the average resistance (R), the low-frequency limit of resistance (R0), the slope of the resistance-frequency curve (S), respiratory elastance (E) and respiratory inertance (I). Similar coefficients (R0', S', E', I'), some of which however have slightly different physiological meanings, were derived from Ztr. R, R0 and R0' were found to be significantly correlated to body height (p less than 0.001) and, independently, to age (p less than 0.05): R (kPa X l-1 X s) = 1.76-5.29 10(-3) height (cm) -4.13 10(-2) age (yr). Elastances were better correlated to height than to age: E (kPa X l-1) = 20.95-0.101 height (cm) and inertances better correlated to age than to height: I (Pa X l-1 X s2) = 4.39-0.128 age (yr). S and S' were not correlated to biometric variables. No difference was found between children living in polluted (n = 36) and nonpolluted (n = 33) areas, except for S which was significantly lower in the first group (p less than 0.01).

Adolescent↗

Comparison of four methods for calculating the total lung capacity measured by body plethysmography.

Static lung volumes were measured plethysmographically one hour apart in healthy subjects (n = 14) and in patients with chronic pulmonary disorders of various etiologies (n = 25). The total lung capacity (TLC) obtained from paired measurements of functional residual capacity (FRC) and inspiratory capacity (IC) was calculated according to the four following methods: 1) average FRC plus the largest IC, 2) average FRC plus the average IC, 3) largest sum of FRC and corresponding IC, and 4) average of individual FRC and IC sums. The data, analysed for average values and for reproducibility in the group as a whole and in the healthy subjects and patients separately indicate that: a) For the group as a whole the largest average TLC values were found with method 3 followed by methods 4 and 1. The differences were statistically significant for all comparisons but one (method 1 vs method 4). A similar pattern was found for the healthy subjects and patients separately. b) For the group as a whole, the one hour reproducibility tended to be worse from method 1 through method 4 but the intermethod differences were not statistically significant. For the healthy subjects, the reproducibility tended to be better for methods 3 and 4 and for the patients this was the case for methods 1 and 2. The average reproducibiltiy of methods 1 and 2 was similar for both the healthy and patient groups and these methods seemed more suitable for TLC calculations. Because it is more widely employed, method 1 is recommended.

Adolescent↗

[The place of the chest radiograph in estimating total lung capacity (author's transl)].

The determination of total lung capacity (TLC) by either the plethysmographic (pleth) or closed-circuit foreign gas (dil) method requires expensive and sophisticated equipment. Since hospitals usually have the facilities to perform chest roentgenograms, we wanted to ascertain if the radiologic method (rad) of BARNHARD et al. [1] could be used in lieu of the more sophisticated methods. Sixty-two men ranging from 21 to 67 years had TLC determined by the plethysmographic method, the closed-circuit foreign gas method in which rebreathing was continued until helium was uniformly distributed throughout the lungs, and the radiologic method. There were 21 normal men, 30 with a clinical diagnosis of chronic bronchitis and 11 with a radiologic diagnosis of emphysema plus chronic bronchitis. The mean value of TLC in the normal men showed no significant differences between the three methods and an excellent correlation between the pleth-rad and dil-rad. In the men with chronic bronchitis, there were no significant differences between the mean TLC of rad (7.166 +/- 1.217 1) and dil (6.704 +/- 1.067 1) of rad and pleth (7.545 +/- 1.165 1). The correlations (p < 0.001) were: dil-rad (r = 0.78) and pleth-rad (r = 0.77). In the men with emphysema, there were also no significant differences between the mean TLC of rad (7.166 +/- 1.217 1) and dil (6.704 +/- 1.067 1) or rad and pleth (7.545 +/- 1.165 1). The correlations (p < 0.001) were: dil-rad (r = 0.78) and pleth-rad (r = 0.77). In the men with emphysema, there were also no significant differences between the mean TLC of rad (8.789 +/- 1.207 1) and dil (7.831 +/- 1.041 1) or rad and pleth (9.403 +/- 1.735 1). The correlations were: dil-rad (r = 0.81, p < 0.01) and pleth-rad (r = 0.91, p < 0.001). This study suggests that in normal individuals and patients with chronic bronchitis or emphysema the radiographic method is a useful and reliable technique for determining TLC when elaborate equipment for measuring lung volumes is not available.

Humans↗

[The sleep apnea syndrome].

The authors presents an pathologic entity whose importance has been outlined in the last few years: sleep apnea syndromes. They insisted on the level of study of this syndrome in western countries. They presents the etiology, the pathophysiology and the main complication and they emphasizes the risks of traffic accidents due to the fall asleep and the cardiovascular complication. The therapeutical possibilities depending on the evolutive stage has been surveyed.

Chronic Disease↗