Search PubMed⌕ Search

Biomedical subjects

D T Reilly

Publications and source records attributed to D T Reilly.

49 records · Page 3Linked to original sources

Transplantation.

Explore the source record for details and available documents.

Humans↗

Fibrinolysis and the prediction of postoperative deep vein thrombosis.

Fibrinolytic activity was measured in 28 patients undergoing elective abdominal surgery in order to assess the value of fibrinolytic activity as a predictive indicator of deep vein thrombosis. Eighty-nine non-smoking adults acted as controls. Fibrinolytic activity was estimated before and during operation, immediately postoperatively and 24 h and 48 h after operation. The onset of deep vein thrombosis was assessed daily for 5 days using 125I-fibrinogen uptake scans. Fibrinolytic activity in 9 patients changed significantly and 7 of these developed deep vein thrombosis. Preoperative assessment of fibrinolytic activity cannot alone predict deep vein thrombosis but changes in the pattern of activity may be of help in defining those at risk.

Abdomen↗

Concurrent exchange of 45Ca and 3H-tetracycline from rat bone in vitro.

Bone from rats sacrified at 2, 5, and 95 weeks of age following 45Ca and 3H-tetracycline labeling in utero or postnatally was placed in solutions of physiological saline, nonradioactive calcium, or tetracycline. This procedure was designed to determine the availability for exchange of 45Ca and 3H-tetracycline from bone mineral in vitro. With time after labeling a gradual decrease occurred in both the nonspecific loss and specific exchange of 45Ca and 3H-tetracycline. 45Ca and 3H-tetracycline in bone could be partially exchanged in vitro with their respective nonradioactive counterparts. Each isotope could be partially exchanged, independently of the other istope. Nonradioactive calcium increased the exchange of 45Ca while suppressing the release of 3H-tetracycline. Molecular 3H-tetracycline exchange occurred to a greater degree than ionic 45Ca exchange and was associated with a small loss of 45Ca. The molecular exchange of 3H-tetracycline with bulk tetracycline did not induce any significant loss of tritium from 3H-tetracycline.

Animals↗

Aging of bone tissue: mechanical properties.

The mechanical properties of machined cortical bone specimens from human femora and tibiae were determined in tension, torsion, and compression for a population ranging in age from twenty-one to eighty-six years. No significant differences were found between the mechanical properties of male and female specimens. Tibial specimens had greater ultimate strength, stiffness, and ultimate strain than femoral specimens. Consistent decreases with age for all mechanical properties except plastic modulus were found in the femoral but not in the tibial specimens. No consistent significant differences in tension properties were found in specimens from normal, osteoporotic, and corticosteroid-treated individuals.

Adult↗