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Biomedical subjects

D Strinović

Publications and source records attributed to D Strinović.

3 recordsLinked to original sources

Short tandem repeat polymorphism at the HUMCD4 and HUMF13B loci in a Croatian population.

Population studies were carried out on unrelated individuals of Croatian ancestry. Genomic DNA was amplified by the polymerase chain reaction (PCR) at the polymorphic microsatellite loci HUMCD4 (n = 105 individuals) and HUMF13B (n = 108 individuals). After horizontal polyacrylamide gel electrophoresis followed by silver staining 6 alleles and 12 genotypes were observed for HUMCD4 and 6 alleles and 13 genotypes could be identified for HUMF13B. Data obtained were in concordance with the prediction of Hardy-Weinberg equilibrium. The allele frequency data were compared with Austrian and Italian population samples and no significant deviations between these populations were observed.

Alleles↗

Acetylcholinesterase in the human frontal associative cortex during the period of cognitive development: early laminar shifts and late innervation of pyramidal neurons.

Laminar preferences in fibrillar acetylcholinesterase (AChE) staining change dramatically in the human frontal cortex during the first postnatal year and perikaryal reactivity is found only in non-pyramidal neurons. The AChE reactivity of layer III pyramidal cell bodies and surrounding fibrillar network begins to develop after the first postnatal year, increases gradually and reaches its peak intensity in young adults, displaying a cluster-like arrangement. These data suggest that AChE-rich elements participate in the innervation of cortical associative neurons and layers during the cognitive development in man.

Acetylcholinesterase↗