Considerations on some anatomo-clinical phenomena of thyroid cancer. Treatment and prognosis. Personal experience with 1515 operated cases.
The authors present a retrospective study on 1515 histologically confirmed cases of thyroid cancer encountered along a period of 30 years of activity. These cases were found among 15,200 patients operated on for thyroid disorders. Of these 1515 cases, 1310 were differentiated carcinomas of the follicular, papillary or trabecular type, 156 nondifferentiated carcinomas and 49 medullary carcinomas. The treatment for all these forms of cancer was a complex one, depending on the clinical stage and the anatomo-pathologic form. The authors advocate total or quasi-total thyroidectomy in all the forms of differentiated cancer, followed by administration of radioactive iodine and hormones. Under these conditions, the prognosis is extremely favourable. For nondifferentiated and medullary cancer the authors propose a wide resection followed by application of X-ray or cobalt and hormonal substitution therapy. The prognosis of these cases is poor.