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Biomedical subjects

D Steiner

Publications and source records attributed to D Steiner.

At least 55 records · Page 3Linked to original sources

[Topography of the upper biceps tendon segment].

26 shoulders are studied by polariscopic and histologic examination. It can be confirmed that the origin of the long biceps tendon is not only at the supraglenoid tubercle, but also y-shaped in the glenoid labrum. This finding can be explained by phylogenetic means. Further details are found during the course of the tendon through the bicipital groove. A mesotenonium is seen regularly. This is fixed either to the roof or the ground of the sulcus by a band of connective tissue. It is shown also, that the roof of the groove is not a ligament (ligamentum transversum humeri) but consists of collagen fibers continuing from the subscapularis and capsular attachment at the lesser tubercle.

Adult↗

Audiotaped versus written administration of the Situational Competency Test.

The Situational Competency Test (SCT) is an audiotaped, verbal role-play measure of coping responses to eight drinking and eight non-drinking situations. The present investigation evaluated the comparability of response scores to audiotaped versus written administrations of the SCT in two samples of alcohol clients. The written administration of the SCT yielded significantly shorter durations of response in both clinical samples, but there were no other significant differences between the administration methods on the other scoring dimensions. Correlations of the audiotaped and written summary scores revealed no consistently significant or meaningful associations. Given the differences in duration, the generally poor correlations between summary scores, and the loss of the latency measure in the written format, we recommend retention of the audiotaped administration for use in research.

Adaptation, Psychological↗

Arterial supply of the human long biceps tendon.

The present study deals with the question whether an insufficient vascular supply of certain areas can be made responsible for ruptures in the biceps tendon. The macroscopic and microscopic examination shows that the blood supply of the tendon in the part most prone to ruptures, that is in the bicipital groove, is guaranteed even in older individuals. It is at least much better than in the intra-articular portion where ruptures are seldom observed. This means that mechanical components such as friction are dominant. The vascular factors seem to play a minor part.

Adult↗

Papillary circulation dynamics in glaucoma.

The ability of glaucomatous eyes to adjust to a sudden increase in intraocular pressure was investigated in nine certain glaucoma cases and in ten normal subjects. The "dynamic provoked circulatory response" (DPCR) was determined by continuously measuring the brightness of the papilla before (baseline), during, and after an abrupt artificial elevation in intraocular pressure. Following the onset of intraocular pressure elevation, the period during which the baseline brightness of the papilla persisted (latency time) was significantly (P less than 0.001) shorter in glaucomatous eyes (0.64 +/- 0.25 s) than in normal eyes (2.39 +/- 0.68 s). This led to the suggestion that the extent to which an eye can adjust to abruptly higher intraocular pressure is measurably reduced in glaucoma. That this effect can be quantified indicates a potentially useful method for detection and follow-up of glaucoma.

Aged↗

[Shoulder and transducer position in sonographic soft tissue diagnosis. Anatomic principles].

The positions of the arm and of the transducer for the sonographic detection of soft tissue disorders of the shoulder have not yet been standardised. Anatomical studies were performed on 16 shoulders in different rotatory positions according to applied sonographic planes. 4 images in 3 different shoulder positions are necessary to evaluate the clinical important areas as completely as possible. With regard to the time and cost involved, this expenditure is acceptable in daily routine work.

Aged↗

A comparison of two ambulatory blood pressure monitors, the Del Mar Avionics Pressurometer IV and the Spacelabs 90202.

The purpose of this study was to evaluate the accuracy of two noninvasive ambulatory blood pressure (BP) monitors, the new Del Mar Avionics Pressurometer IV (PIV) and the second generation Spacelabs 90202. Two sets of comparisons were made between two trained observers and the monitors on 17 normotensive and 28 hypertensive subjects. The result of the first comparison showed that the average difference between observers and the PIV was 1.2/-2.2 mm Hg for systolic and diastolic BP. Comparisons of both monitors to the observers showed differences of 0.9/1.0 mm Hg for the PIV and 0.3/0.8 mm Hg for the 90202 (systolic/diastolic). Correlations between the average observer reading and the monitors over both sets of comparisons ranged from 0.90 (diastolic 90202 vs observer) to 0.98 (systolic PIV vs observer). The percentage of readings within 5 mm Hg between observer and monitor over all comparisons ranged from a low of 68% (90202, systolic and diastolic) to a high of 83% (PIV, diastolic). In general, both devices are satisfactory and reliable machines for ambulatory BP monitoring, but each has a slightly different bias compared to auscultatory readings.

Adult↗

Bioconstruction of the extrahepatic biliary duct system in minipigs. Comparing normal condition with experimental obstruction.

The extrahepatic biliary duct system is subject to a particular bioconstruction to secure its bile transport function. The dominant structure of the bile duct wall is a network of collagen fibres harboring muscle-fibre bundles. The collagen fibres are virtually inelastic, volumes can be changed only by rearranging the network. The ducts show different spatial arrangements of the fibres causing different extents of dilatation during obstruction. Extreme dilatation might cause a rupture of the network, and deficient postoperative retonisation could be the result.

Animals↗

Collagen fiber arrangement of the human shoulder joint capsule--an anatomical study.

The polariscopic examination of isolated shoulder joint capsules shows that the entire capsule does not have a homogeneous collagen structure. Most of the capsule is characterized by regular collagen fibers which cross at an obtuse angle in the area of the musculus supraspinatus and at an acute angle in the area of the m. infraspinatus. The density of the collagen network increases from the medial to the lateral part. Deviating from this basic pattern of the joint capsule, there is a different collagen texture in the area between the m. supraspinatus and the m. subscapularis. This texture has dissociated, rarefied and irregular collagen fibers. This means that the area--in comparison with the remainder of the capsule--is characterized not only by missing reinforcing ligaments but also by a deviating pattern of the collagen fibers. This different collagen structure is already existent in the fetus.

Adult↗

[Current and known aspects of the arterial supply of the rotator cuff].

The basic arterial supply of the shoulder is well known, some details for example the supply of the m. supraspinatus are not studied yet. Preparation of shoulder-specimens after injection of silicone-caoutchouc are done to examine the vascular system. The arterial supply of the shoulder is described as a system of four rings. The results are discussed in combination with the literature.

Arteries↗

Should gastric carcinoid tumors associated with pernicious anemia be treated aggressively?

Two patients with pernicious anemia developed gastric carcinoid, one 20 years and the other 1 year after diagnosis of pernicious anemia. One of the patients underwent successful resection of the tumor, while the second, with diffuse gastric carcinoid, was managed conservatively. She is well and asymptomatic 32 months after the diagnosis. We discuss the dilemma in management of gastric carcinoid associated with pernicious anemia.

Aged↗

Three mutant insulins in man.

We have previously identified a structurally abnormal insulin in the serum and pancreas of a middle-aged man with diabetes mellitus which arose from a leucine for phenylalanine substitution at position 24 or 25 of the insulin B chain; further analysis of the patient's leukocyte DNA showed that one of the patient's insulin alleles had undergone mutation resulting in loss of an MboII restriction site normally present in the human insulin gene. Two additional and unrelated patients with the same clinical syndrome have now been identified (ref. 4 and unpublished results). All of these patients showed hyperglycaemia typical of diabetes and with marked hyperinsulinaemia typical of insulin resistance, but all three show normal tolerance to exogenously administered insulin. As the opportunity of examining pancreatic tissue from patients suspected of secreting insulin variants is rare, we have developed a method combining HPLC and radioimmunoassay to identify insulin variants isolated from human sera. By this method we have shown that all three patients noted above secrete structurally variant and chemically distinct insulins. In correction of our original assignment, one is identified as [LeuB25]insulin.

Amino Acid Sequence↗

Busulfan-induced hemorrhagic cystitis.

We report a case of severe hemorrhagic cystitis induced by prolonged busulfan therapy. The clinical course and pathological results were similar to irradiation and cyclophosphamide cystitis. Only 1 such case has been described previously. Although hemorrhagic cystitis induced by busulfan is a rare complication it should be considered in the differential diagnosis and busulfan should be discontinued immediately.

Adult↗

[Nerve sheath tumors: malignant schwannoma (author's transl)].

The morphology and biology of tumors of the nerve sheath show rather heterogeneous aspects. In most the site of origin seems to be the Schwann's cells. Essentially these tumors can be differentiated into three groups: 1. malignant schwannoma, 2. neurinoma, and 3. neurofibroma. Although the Schwann's cell is the common origin, the three different tumors can be well differentiated histologically with the exception of malignant schwannoma and spindle cell sarcoma. The clinical symptoms are determined by the location of the tumor and are without general characteristics. The treatment of choice is always radical surgery. In addition, radiation and chemotherapy are indicated in special cases.

Diagnosis, Differential↗

Diagnosis of pancreatic carcinoma by means of endoscopic retrograde pancreatography and pancreatic cytology.

Endoscopic retrograde pancreatography (ERP) combined with pancreatic juice cytology, was performed in 14 patients with pancreatic carcinoma confirmed at subsequent laparotomy. ERP demonstrated duct abnormalities that were diagnosed as carcinoma in 86% of the cases and as suggestive of carcinoma in another 14%. Cytology was positive in 86% and suspicious in 7%. By combining both methods, all 14 carcinomas were correctly identified. Thus, in our hands, ERP and pancreatic juice cytology proved to be the most sensitive and reliable methods in detecting pancreatic carcinoma. On the basis of these promising results it is proposed that pancreatic juice cytology, which is a no-risk method, should be employed in all elderly patients with unexplained abdominal complaints, to screen them for early pancreatic carcinoma.

Carcinoma↗