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Biomedical subjects

D Shoch

Publications and source records attributed to D Shoch.

At least 19 recordsLinked to original sources

Optic disk size in ischemic optic neuropathy.

We measured the horizontal diameter, vertical diameter, and area of the optic disk in fellow eyes of patients with unilateral nonarteritic ischemic optic neuropathy and in control eyes without ocular disease. The fellow eyes of patients with anterior ischemic optic neuropathy had a smaller horizontal than vertical disk diameter (P less than .05), a difference not present in controls. Both the horizontal disk diameter and the disk area were significantly smaller in fellow eyes of patients with anterior ischemic optic neuropathy than in controls (P less than .05). There was no statistical difference in the vertical disk diameters between the two groups. Our findings suggest that a small disk area along with a horizontal shortening of the scleral canal can lead to crowding of optic nerve fibers, predisposing to a circulatory compromise of the optic nerve head in non-arteritic anterior ischemic optic neuropathy.

Adult

Secondary angle-closure glaucoma after central retinal vein occlusion.

A 65-year-old man developed unilateral nonrubeotic secondary angle-closure glaucoma after central retinal vein occlusion. Therapy was nonsurgical and included medical control of the intraocular pressure. The anterior chamber eventually deepened and panretinal photocoagulation was later necessary because of developing rubeosis iridis and neovascularization of the optic disk. Secondary nonrubeotic angle-closure glaucoma from central retinal vein occlusion must be distinguished from rubeotic glaucoma or pupillary-block glaucoma so that inappropriate medical or surgical treatment can be avoided.

Aged

Cataracts and macular degeneration.

The intraocular lens restores general vision and some degree of independence and mobility to patients with dense cataracts and macular degeneration. The patient, however, must be repeatedly warned that fine central vision, particularly reading, will not be possible after the surgery. An aphakic spectacle leaves such patients a narrow band of vision when superimposed over the macular lesion, and contact lenses are too small for the patient to manage insertion without help.

Aged

Jules Stein, MD.

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History, 19th Century

Central areolar pigment epithelial (cape) dystrophy.

A family with a unique hereditary macular dystrophy is presented. The disorder is transmitted as an autosomal dominant trait having high penetrance and variable expression. The characteristics of this dystrophy are: childhood onset; nonprogressive areolar depigmentation of the central macula; and with the exception of one eye with a macular hemorrhage, normal vision acuity and retinal-function studies.

Adolescent

Differential effects of inhibitors of monoamine oxidase Types A and B on the adrenergic system of the rabbit iris.

Topical instillation of inhibitors of monoamine oxidase Types A and B into the rabbit eye, followed by the administration of a releaser of monoamines (Ro 4-1284), induces strong and sustained dilation of the iris. The mydriatic pattern differs markedly with A- and B-inhibitors and with the duration of the inhibitor treatment. The Type B inhibitor, deprenyl, prevents the degradation of exogenous 2-phenylethylamine and possibly of the endogenous amine X capable of releasing monoamines from a compartment less accessible to Ro-1284.

5-Methoxytryptamine