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Biomedical subjects

D Shapiro

Publications and source records attributed to D Shapiro.

At least 235 records · Page 13Linked to original sources
PubMed1967

Diagnosis of gaucher's disease and niemann-pick disease with small samples of venous blood.

Enzymes which catalyze the hydrolysis of glucocerebroside and sphingomyelin have been demonstrated in preparations of washed human white blood cells. The level of activity of these respective enzymes is markedly decreased in leukocyte preparations obtained from patients with Gaucher's and Niemann-Pick diseases. Assay of these enzymes may be useful in the differential diagnosis of the sphingolipidoses.

Adolescent↗
PubMedDate not supplied

Postprandial ambulatory blood pressure and heart rate effects in healthy elderly adults.

The goal of the study was to investigate postprandial blood pressure (BP) and heart rate (HR) changes among the elderly in the natural environment by means of ambulatory BP monitoring. A sample of 26 men and 27 women, 65-83 years of age, was studied 90 min before and during the 120 min following the initiation of the dinner meal on two separate days. Subjects all lived in their own homes, had no major disorders, and were not taking any medication. Sitting BP decreased significantly from 61-120 min after the initiation of eating (drop of 6.5/8.0 mmHg from pre-meal values). Heart rate showed an increase of 4 bpm at 31-90 min after beginning eating. Decreases in BP did not appear to be a function of the subject's state of arousal, time of meal, or level of activity. Cardiovascular changes in response to eating in a natural setting were comparable to those we reported in a previous study under controlled conditions. It is important to be aware of these changes when one is evaluating 24-h BP.

Aged↗