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Biomedical subjects

D Sengupta

Publications and source records attributed to D Sengupta.

At least 73 records · Page 4Linked to original sources
PubMed1980

Platelet and erythrocyte-membrane adenosine triphosphatase activity in depressive and manic-depressive illness.

An investigation of Mg2+ and (Na+ + K+)-dependent adenosine triphosphatase (ATPase) activities in the platelet and erythrocyte membrane of 44 depressive and 44 manic-depressive patients was carried out before and during (for 3 weeks to less than 1 year) drug treatment. When compared with normal controls (n = 43), the patients showed significantly elevated enzyme activities during both the drug-free and drug treatment periods. No remarkable changes in enzyme activities were observed between the drug-free and drug treatment (even long-term drug treatment) periods. Results suggest an alteration of cell-membrane activity, which may reflect changes in (1) ATP level, (2) cationic balance, (3) membrane phospholipid, or some combination thereof.

Adenosine Triphosphatases↗
PubMed1976

Autoregulation of cerebral blood flow during controlled hypotension in baboons.

The effect of graded, progressive hypotension on the autoregulation of cerebral blood flow was studied in anaesthetised baboons. Progressive hypotension was produced over a period of four to five hours, either by graded haemorrhage or by the administration of increasing concentrations of hypotensive drugs. During haemorrhagic hypotension autoregulation was maintained until the mean arterial pressure had decreased to 65% of its baseline value, below which cerebral blood flow was pressure passive. In those animals subjected to drug-induced hypotension, autoregulation persisted to lower levels of mean arterial pressure (35-40% of baseline). It is postulated that under conditions of haemorrhagic hypotension, constriction of the extraparenchymal cerebral vessels in response to sympathetic stimulation decreases the possible range of autoregulation in the anaesthetised baboon.

Animals↗
PubMed1975

Osteopetrosis.

Explore the source record for details and available documents.

Adolescent↗