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Biomedical subjects

D Seifert

Publications and source records attributed to D Seifert.

33 records · Page 2Linked to original sources

Seven years of experience with the centrifugal pump in patients with cardiogenic shock.

From September 1987 to September 1994 61 patients between 29 and 78 years of age received mechanical circulatory support by means of the Biomedicus centrifugal pump. The patients were divided into three groups by indication: Group I included 15 patients with early postcardiotomy cardiogenic shock and 24 patients with late postcardiotomy cardiogenic shock. Group II 11 patients with therapy-resistant cardiogenic shock following acute myocardial infarction, and Group III 11 patients with cardiogenic shock of other etiologies. Duration of support was 1 to 347 hours. Survival rates were 46.7% and 33.3% in patients with early and late postcardiotomy cardiogenic shock, respectively (Group I), 27.2% in Group II, and 18.1% in Group III. Most frequent complications were bleeding (40%, 58%) and acute renal failure (26.7%, 29.2%) in Group I and multiple organ failure in Groups II and III (64% and 45.5%). Major causes of death were bleeding and multiple organ failure in Group I (37.5%) and multiple organ failure in Groups II and III (87.5% and 50%). Groups II and III (87.5% and 50%).

Adult↗

Transsexual development of a patient with Klinefelter's syndrome.

Although the psychosexual development of patients with Klinefelter's syndrome is often delayed, the sexual identity is generally male. This paper reports on a 56-year-old patient whose initially good psychosocial integration gave way to a transsexual development with a meanwhile clearcut female sexual identity as the consequence of a personal crisis situation. This case report illustrates the interaction of biological and psychodynamic etiological factors.

Chromosome Aberrations↗

[The orthodontic classification of impacted canines with special reference to the age at treatment, the angulation and dynamic occlusion].

The literature regards the surgical-orthodontic treatment of ectopic canine as being the optimal therapy. This treatment, however, often takes a long time and disturbances in the functional occlusion often occur after treatment is ended. For this reason it was decided to evaluate the treatment's success taking into consideration age at time of treatment, angulation, and functional occlusion. The post-treatment examinations of 66 patients up to five years after treatment reveal above all a correlation between treatment success and age at the time treatment begins. In addition patients with class II/2 and tooth aplasia were identified as constituting a risk group. These malocclusions, therefore, are a sign that there is a risk of ectopic canines. The occlusion type in laterotrusion movement provides group guidance. Beginning treatment after age 25 years should be critically evaluated, because the treatment period is prolonged.

Adolescent↗

[The long-term observation of alveolar bone blood flow during tooth movement with the aid of skeletal scintigraphy in an animal model].

We observed in eleven dogs the blood flow in the alveolar bone during the tooth movement with the bone scintigraphy for one year. Additional we used for histological evaluation polychrome sequence marking and for improving of therapy electrostimulation. There is a correlation between tooth movement and blood flow. Four to six weeks after beginning tooth movement and blood circulation are reduced although the applied force was continuous all the time. This is an advice for stress interruption during treatment. Electrostimulation improves the conditions for tissue regeneration because the lifetime of osteoblasts is prolonged.

Alkaline Phosphatase↗

[Comparison of location between nasion and orbital points on soft tissue and on bony structures, in articulatory technique].

A skin projection of the orbitale as palpated through soft tissues was designated on the left cheek of 22 subjects. The nasion, orbitale and cephalostat nasion direction medium were plotted on transparent paper after teleroentgenography. Mutually parallel lines were drawn through the points, the line obtained on the construction of the nasion direction medium used as a basic one. Distances between the lines were measured and results statistically processed. Transfer of the model into the articulatory region by means of the orbitale and buccal arch nasion direction appeared not to orientate reliably the model according to reference planes of the head. Our results are consistent with literature data available.

Adolescent↗

[Evaluation of the reconstruction of occlusal plane by use of Ponans angle].

In this study, teleroentgenocephalograms of 34 subjects with at least 20 natural teeth were used. Correlation between the angle formed by linking the PORION-NASION-SPINA NASALIS ANTERIOR (PONANS angle) points and the angle made by Frankfort horizontal and occlusion plane was studied. The coefficient of correlation was 0.1263. It is considered that there is no correlation if the coefficient of correlation is less than 0.5. Thus, there was no correlation in the study sample, which is consistent with the results reported by Karkazis and Polyzois, but in disagreement with those published by Monteith. In our sample, the occlusion plane could not be oriented in the articulatory space or in toothless mouth by means of the method proposed by Monteith.

Adolescent↗

[Coronary artery stenoses close to the ostia after mediastinal irradiation].

A 42-year-old man who 16 years previously had had mediastinal radiotherapy (total focal dosage of 52 Gy) for a malignant lymphoma, developed chest pain on mild exertion. Coronary arteriography during a diagnostic cardiological work-up revealed a 50-70% stenosis of the right coronary artery near its origin and a 90% stenosis in the main left coronary artery. Except for being slightly over-weight (85 kg at a height of 181 cm) there were no risk factors for coronary heart disease and there was no evidence for arterial disease elsewhere. A double aortocoronary vein graft was placed to the right coronary artery and the interventricular branch of the left coronary artery. The postoperative course was unremarkable and the patient has resumed his occupation. This report emphasizes that, in case of atypical chest pain after mediastinal radiotherapy, coronary heart disease as a late complication should be considered.

Adult↗

[Use of rectal temperature-time of death nomograms at the scene of death].

The application of the rectal temperature time of death nomogram at the scene of death by 11 authors from 6 lego-medical institutes resulted in a standard deviation of the differences between nomographic and real death time of +/- 1.3 h in 46 cases (group I) with met requirements and clearly defined points of contact, nevertheless, including 9 cases with a more progressive cooling (0.5 greater than Q greater than or equal to 0.2). In cases with a real death time of more than 4h (N = 26) the standard deviation was +/- 1.0 hours corresponding to permissible variation of 95% of +/- 2.0 hours. Consequently, the permissible variation of 95% was much smaller than that suggested by the nomogram. The nomographic death time interval did not agree with the real one in 5 cases out of additional 30 cases with recognizably unsure points of contact (group II).

Body Temperature Regulation↗

[Midazolam--a forensic problem drug?].

Benzodiazepine derivates can cause transient global amnesia even when administered in therapeutical doses. As amnesia seems to be more frequent than supposed, it is relevant for traffic medicine. We shall discuss forensic cases in which Midazolam amnesia was suspected with special attention to the interpretation of toxicological data.

Accidents, Traffic↗

Reliability of intraoperative flow measurements to determine early graft patency with simultaneous introduction of a new method for distal coronary artery run-off capacity.

Intraoperative measurements of blood flow were made in 44 patients in whom a total of 112 venous bypass grafts were inserted. Blood flow through the graft was measured by a standard electromagnetic device as well as by a new method, consisting of a roller pump run-off system. At an average of 5 months after operation all patients underwent control coronaro-angiography. Overall patency-rate was 86.6%. Using the standard method mean flow in the patent grafts was 78 ml/min and 39 ml/min in the occluded grafts. Using the new run-off method mean flow in the patent grafts was 142 ml/min and 78 ml/min in the occluded grafts. It is concluded that measuring distal coronary artery run-off capacity provides a reliable index for predicting patency rate. For several reasons roller-pump run-off measurement has advantages over the generally used electromagnetic measurements.

Adult↗