Search PubMed⌕ Search

Biomedical subjects

D Schapira

Publications and source records attributed to D Schapira.

69 records · Page 4Linked to original sources
PubMed1986

Trochanteric bursitis: a common clinical problem.

In 72 patients followed for two years, the diagnosis of trochanteric bursitis was based on precise clinical signs without significant contribution from laboratory tests or radiologic signs. In six of the patients (8.3%) the bursitis was an isolated condition of unknown origin. Six other patients had rheumatoid arthritis without involvement of the ipsilateral hip joint. The remaining 60 patients (83.4%) had pathologic conditions of the adjacent areas, such as symptomatic lumbar spine arthrosis or ipsilateral hip damage, conditions that often mask the actual source of pain and disability. A rapid and prolonged improvement of the pain and disability caused by the bursitis was achieved in all 65 patients (90.3%) treated by local corticosteroid and anesthetic infiltrations: in 48 patients after one, in 13 after two and in 4 after three local treatments. Local corticosteroid infiltration proved to be the treatment of choice as well as a diagnostic test.

Adult↗
PubMed1985

Neonatal spinal muscular atrophy presenting as respiratory distress: a clinical variant.

Respiratory distress from diaphragmatic and intercostal muscular weakness was the presenting feature of two neonates with progressive spinal muscular atrophy, leading to death in the first 2 months of life. This atypical feature provides evidence of heterogeneity within the commonly used clarification of type 1 spinal muscular atrophy.

Diagnosis, Differential↗
PubMed1984

Cholestatic jaundice induced by gold salts treatment clinical and immunological aspects--report of one case and review of the literature.

Hepatotoxicity is a rare complication of treatment with gold salts. The clinical and laboratory features are those of cholestatic jaundice and other diagnostic possibilities must be ruled out. Gradual recovery after withdrawal of the drug is the rule. We report a case and review previous literature with emphasis on the diagnostic value of the lymphocyte transformation test.

Arthritis, Rheumatoid↗
PubMedDate not supplied

The impact of current use of hormone replacement therapy on prognostic factors and surgical treatment of new breast cancers.

When postmenopausal women were diagnosed with breast cancer while taking hormone replacement, no adverse effects were noted in either clinical or prognostic factors when compared to a similar group not on hormones. Younger age at diagnosis and an increased chance of carcinoma in situ were noted in those on hormones. A surveillance or observational bias is one explanation for these findings. A promotional effect of hormone replacement therapy could not be eliminated based on this study.

Age Factors↗
PubMedDate not supplied

Severe transient osteoporosis of the hip during pregnancy. Successful treatment with intravenous biphosphonates.

A young woman with transient osteoporosis of the hip (TOH) during pregnancy, severe pain, physical disability and marked generalized osteoporosis was treated with intravenous biphosphonates with prompt beneficial effects on both clinical symptoms and bone density. The features of this rare and sometimes underdiagnosed condition are reviewed. Intravenous biphosphonates seem to be an effective therapy for TOH.

Absorptiometry, Photon↗
PubMedDate not supplied

Seasonal distribution of relapse onset in rheumatoid arthritis and spondyloarthropathy: the possible effect of the solar factor.

BACKGROUND AND OBJECTIVE: The seasonal effect on the relapse of rheumatoid arthritis and spondyloarthropathies is still unclear. To assess the seasonal distribution of relapse onset in rheumatoid arthritis (RA) and spondyloarthropathy (SpA) and its association with solar factors. METHODS: The monthly distribution of relapse onsets during the years 1998-2000 was retrospectively chart reviewed in 364 patients. In 1998 a total of 131 patients were studied; 60 with seropositive (sp) RA, 30 with seronegative (sn) RA and 41 with SpA; 113 patients in 1999: 44 with spRA, 38 with snRA and 31 with SpA; 120 patients in 2000: 56 with spRA, 38 with snRA and 26 with SpA. All of them were treated in the Department of Rheumatology, which serves the population of northwestern Israel. Solar activity was analyzed according to the "Solar Terrestrial Activity Report Charts 1998-2000". The Central Israel Bureau of Statistics provided the sun global radiation data. Data was assessed during the summer (April-September) and winter (January-March, October-December). The correlation between the monthly distribution of disease relapses and solar factors was measured (SPSS-10 for WIN). RESULTS: Relapses in spRA patients occurred mostly during the summer months with peak activity during the month of July 2000. Single monthly peaks of spRA relapse onset were noted in January 1998-1999 and April 1998 and for snRA in January 1998 and June 2000, but there were no seasonal differences for spRA, snRA and SpA in 1998-1999 and for snRA and SpA in 2000. Relapses in spRA patients were associated with a summer bias of increased solar activity and global solar radiation in 2000 compared with lower peak solar activity in 1998-1999. Furthermore, in 2000 we found a significant correlation of the spRA monthly relapse count to solar activity (p = 0.005) and global sun radiation (p = 0.048) unlike snRA and SpA. No above-mentioned association and correlation was noted in 1998-1999. We revealed mild negative correlation (p = 0.046) of SpA relapse count only to peak solar flux (PSF) by analysis of data for 1998-2000 as one united group. CONCLUSIONS: Relapses were more frequent during the summer of 2000 (May-June-July) in spRA but not in snRA and SpA. The reasons are still unclear. No seasonal differences were observed in 1998-1999. Enhanced solar activity in summer-2000 compared with 1998-1999 may be inferred to be the proposed cause but coincidence may occur as well. Outbreak in RA and SpA was not registered despite increased peak solar activity in 2000. We observed mild evidence of reciprocal relation between SpA relapsing and solar activity during 1998-2000. Solar and any other possible contributory factors remain still to be elucidated.

Arthritis, Rheumatoid↗
PubMedDate not supplied

Azathioprine fever.

Explore the source record for details and available documents.

Aged↗
PubMedDate not supplied

Pulmonary injury induced by gold salts treatment.

Pulmonary damage is one of the rare complications of gold salts therapy. The reaction is that of drug hypersensitivity. The clinical and radiological features as well as the respiratory function tests are that of an interstitial lung disease. This condition is described in four patients and its main features are discussed in the light of the relevant literature. The importance of an early diagnosis is emphasized. Most of the patients recover after the withdrawal of the drug and during corticosteroid treatment.

Adrenal Cortex Hormones↗