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Biomedical subjects

D Sapunar

Publications and source records attributed to D Sapunar.

24 records · Page 2Linked to original sources

Effects of hyperbaric oxygen on rat embryos.

The aim of the study was to investigate the toxic effects of hyperbaric oxygen (HBO) on rat embryos. Two groups of Fischer pregnant rats were exposed to oxygen at pressures of 324 and 426 kPa for 90 min per day for 5 consecutive days (8-12 days of gestation). The third group was exposed to normobaric oxygen for 12 h on the eighth day of gestation. Two control groups were used; the first was comprised of intact and the second of sham-treated animals. The HBO treatment did not significantly affect maternal weight gain or reduce litter size, nor did it induce any embryonic abnormalities. However, the fetal body weight was reduced and the placental weight increased in the groups exposed to HBO at pressures of 324 and 426 kPa. When female fetuses which had been exposed to oxygen at 324 or 426 kPa were compared to the intact control group, a reduction in wet weights of 9.2 (p < 0.05) and 12.1% (p < 0.01), respectively, was noted. Male fetuses exposed to oxygen at 324 and 426 kPa displayed a reduced body weight of 11.7 (p < 0.01) and 16.6% (p < 0.01), respectively. Placental weight was increased by 18.9 (p < 0.01) and 23.6% (p < 0.01) in the groups exposed to oxygen at 324 and 426 kPa, respectively. These data suggest that HBO, either at 324 or 426 kPa, is not potent at inducing malformations and that the largest embryotoxic effects are upon fetal body weight and placental weight.(ABSTRACT TRUNCATED AT 250 WORDS)

Animals↗

[The Medical School of Split--overview of its activity from independence until today].

The aim of this report is to describe the current status of medical education program in the University of Split Medical School and to investigate readiness to accept modern trends in medical education. The report comprises the four-year period, since establishment of independent medical school up to day. The crucial elements of the high education reform with special emphasis on medical education are included in the report. The development of the faculty is still burdened with lack of personnel, poor market orientation and relatively small scientific production. The financial report, scientific production data, and information about student performance are also included. The decision that all exams must be passed before enrolment to the next academic year showed full justification. Although exposed to strong criticism, our new curriculum implemented four year ago is still unchanged. Joint effort of all medical schools in Croatia has to be directed to the follow up of all information important for the medical education, development of the quality assurance mechanisms and to enhancing state examination, standard for the evaluation of the medical schools' quality.

Croatia↗

[Blunt heart injuries and diagnostic difficulties].

The authors present their experiences with blunt heart injuries treated in the University Surgical Hospital in Split, Croatia. The diagnostic approach hospitalization and follow-up of these patients are described. The heart contusion was diagnosed using several repeated electrocardiographic and enzymatic tests combined with two-dimensional echocardiography. We treated 67 patients with heart contusions within two-year period. Out of them, 63 (94%) were dismissed from the hospital as cured, and 4 (6%) of them died. Results of treatment depend on the severity of injury, but also on a timely and adequate management.

Adult↗

[Reasons for founding a University of Split Medical School].

This article advocates a transformation of the Zagreb University School of Medicine Split Branch into an independent medical school, i.e. Split University School of Medicine. The difficulties stemming from the present organizational scheme of work of Medical School in Zagreb and its Split Branch, and particularly from the complex political and geographical relations, are a heavy burden thwarting the work of both institutions. On the other hand, the medicine in Split has all indicators which should guarantee a successful work of an independent medical school in the city. These indicators concern capacities of the local premises, number and quality of the faculty, long tradition of medical education, and recent educational, medical and scientific results. A particularly important argument is an immense need of southern Croatia and the neighbouring parts of Bosnia and Herzegovina for medical education. A careful analysis showed that the independent Medical School would neither impose additional expenses from the part of the Republic, nor cause an overproduction of physicians. A state examination organized so that the results of the candidates could be quantified, would provide an unequivocal answer to the question on the number of medical schools needed in Croatia and, more important, the picture of the quality of their work.

Croatia↗

[The Internet in medicine].

Internet is a global computer network that connects numerous smaller computer networks. During the last several years Internet has become enormously popular and the number of users in the world has increased to 30 million. Internet is now a major tool for sharing computers resources and for communication between individuals and scientific institutions. Internet also contains enormous quantities of medical information and knowledge. During the last several years, many new sites have emerged on the Internet, offering exciting and useful information on medical practice, research, decision support, and education. This article describes the history of the Internet, the various ways of connecting to it and some of the tolls particularly useful for medical doctors. This article provides a tutorial how to access the important medical resources that Internet offers to the clinicians, teachers, and researcher. Also this article will provide description of access, structure and contents of the two World Wide Web locations. BioMedNet is a location designed for biomedical research. It was chosen because of its exceptional quality and importance for researchers. The second described location is CHORUS, developed for continuing education in radiology.

Computer Communication Networks↗