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D Safran

Publications and source records attributed to D Safran.

59 records · Page 4Linked to original sources

[Effects of anesthesia induction with propofol on plasma renin activity and atrial natriuretic factor secretion. A preliminary study].

The authors have noted a substantial increase in plasma renin activity, when the patients were induced with propofol (2.5 mg.kg-1). Although a direct or an indirect effect of propofol may be suggested, the design of this study is not helpful in pointing out the responsibility of the drug in the observed effects. Further studies including peripheral vascular resistance measurements should be undertaken.

Adult↗

[Comparative use of thiopental and methohexital in patients anesthesized for E.N.T. endoscopy. Apropos of 60 cases].

The clinical effects of methohexital versus thiopental are studied in 60 randomized patients anaesthetized for E.N.T. endoscopy or laser surgery of the larynx. Thiopental is injected by I.V. bolus (5 mg/kg) and methohexital is administered by continuous infusion (0.1 mg/kg/min). Fentanyl is the analgesic and succinyl-choline is used for curarisation. All patients are ventilated by a conventional ventilator or by high frequency ventilation. Side-effects, extubation time, and recovery estimated by the Newman-test modified by Weber are studied. The only difference between methohexital and thiopental is a better recovery-score at 30 minutes for the methohexital group.

Adult↗