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D S Davis

Publications and source records attributed to D S Davis.

82 records · Page 5Linked to original sources
PubMedDate not supplied

Reactivity of antibodies to core glycolipid with gram-negative bacteria.

Studies of the cross-reactivity of antibodies to core glycolipid with assorted isolated, heterologous lipopolysaccharides (LPSs) confirm the conservation of core glycolipid epitopes among gram-negative bacterial species. However, the accessibility of core glycolipid epitopes to antibody in the intact bacterial cell may be affected by the cell surface structure. In studies with 125I-labeled monoclonal antibodies to core glycolipid that cross-react with isolated LPS, the degree to which antibodies can bind to LPS in the outer membrane of intact, viable, gram-negative bacterial cells was found to vary with the strain of bacteria tested. Sequestration of bacterial cell-bound LPS from antibody was confirmed in a smooth strain of Escherichia coli by means of immunoelectron microscopy. The inability of antibody to bind to membrane-bound LPS suggests that such sequestered LPS may also be unable to effect toxicity in the infected host until liberated by bacterial cell breakdown.

Antibodies, Bacterial↗
PubMedDate not supplied

Genetic evidence of Dobrava virus in Apodemus agrarius in Hungary.

Using nested polymerase chain reaction, we sequenced Dobrava virus (DOB) from the rodent Apodemus agrarius in Hungary. The samples we isolated group with DOB samples previously isolated from A. flavicollis. This grouping may indicate host switching.

Animals↗
PubMedDate not supplied

Genetic dilemmas and the child's right to an open future.

Although deeply committed to the model of nondirective counseling, most genetic counselors enter the profession with certain assumptions about health and disability-for example, that it is preferable to be a hearing person than a deaf person. Thus, most genetic counselors are deeply troubled when parents with certain disabilities ask for assistance in having a child who shares their disability. This ethical challenge benefits little from viewing it as a conflict between beneficence and autonomy. The challenge is better recast as a conflict between parental autonomy and the child's future autonomy.

Adult↗