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Biomedical subjects

D S Chernavskiĭ

Publications and source records attributed to D S Chernavskiĭ.

At least 19 recordsLinked to original sources

[New biophysical technologies in the early diagnosis of organ pathology].

Kinetic electropuncture diagnosis (CASKED) is the advancement of Voll's method and is characterized by a basically new procedure to apply an electrical signal to the acupuncture points (AP). This method records and analyzes not only the amplitude of AP potential, but its temporal kinetics (in the range up to 100 seconds), he characteristic times of kinetic changes are used as diagnostic signs. CASKED makes it possible to make a direct diagnosis by taking into account the localization and characteristic features of a pathological process and to access changes in a patient's condition during treatment.

Acupuncture↗

[Instability and stability in biological morphogenesis].

The concept of morphogenesis is determined and the mathematical image of the developing system is considered. A certain amount of stable and unstable states and slow changes of the potential relief (parameters) are inherent in the latter. The developing systems are intermediate between the deterministic and statistic ones. They are distinctly multiple-levelled. The microprocesses of morphogenesis and the laws of macromorphogenesis are described, the instabilities and stable periods of morphogenesis are considered. All of them in the multiple-leveled system tend to the formation of through hierarchies, or cascades, where the upper levels parametrize the lower ones. This tendency increases as the evolutionary progress proceeds. The genetic regulation is considered also as a parametric regulation in the domains of instabilities. The approach contemplated may be considered both as the generalization of the available data and as the programme of investigation, more adequate to the biological reality than the causal-analytical methodology.

Animals↗

[Minimal mixture principle as a method of choosing the form of a dynamic model].

The extremality principle for molecular processes in biological systems is considered. The principle is based on an assumption that the main function of biological processes is the separation of the "product" from the "scheme". The form of the dynamical model of the process is determined from the requirement of the "minimum mixture". As an example Selkov's model of glycolysis is considered.

Mathematics↗

[Generation of valuable information and the problem of goal self-setting in living systems].

The problem of origination of capacity for goal self-setting is discussed. It was shown that the definition "goal" in living systems differs from the definition "target function" in physical problems concerned with nonliving systems. It was also shown that the main goal of the elements of a system is the storage of information. In biology, this goal is the extension of the principle of struggle for existence. Conditions were determined that the dynamic system describing the goal self-setting process must satisfy. It was shown that living systems meet these conditions. In inorganic nature, such systems may also arise but only as a result of long-term evolution, after which they become living.

Biological Evolution↗

[The study of the mixing layer by the point image method].

The properties of the mixing layer in dynamic systems were studied by the example of a mathematical model of the cubic image type. Its role in the generation of information and the evolution of its significance was shown. At the moment of generation, information is of zero significance, and this significance then increases. A criterion of efficiency was proposed, and the optimum moment of making a decision in creative work was determined. It was shown that the increase in the variability of the parameters of a living system upon entry into the mixing layer and its decrease upon exit can serve as objective indicators of the transition of the system from one dynamic regime (attractor) to another.

Algorithms↗

[Bimodal changes in the germination of seeds subjected to heat treatment].

Novel explanation is proposed for the improvement of low quality seeds by pre-sowing treatment with factors of various nature (heat and sonic treatment, electrical field of corona discharge, laser irradiation). The increase in seed germination percentage is caused by slowing-down of seed water uptake as a result of closing the aquaporin water canals.

Aquaporins↗

[The "protein-machine" concept and its consequences].

Analysis is presented of the concept "protein-machine" and implying consequences, both of theoretical and experimental character. The approach "protein-machine" is compared with other approaches--"coherent excitation", "molecular dynamics" and "limited diffusion". In terms of the approach "protein-machine" valuable information inserted in the biological macromolecule and determining its functions is taken into account. It reflects the biological specificity and at the same time removes mystic shadow from this concept.

Enzymes↗

[Application of synergetics to the theory of ontogenesis (on the parametric control of development)].

Applications of synergetics to ontogenesis are discussed. In terms of synergetics, the choice between the concepts of power and parametric control and the description of parameters and dynamic variables of ontogenesis are among the main tasks of the theory of ontogenesis. Examples are provided for multipotency and variability which suggest the parametric control of development. A suggestion is put forward concerning the parameterizing role of directive inductors. Possible ways of overcoming the ambiguity inherent in the parametric control are considered. A general scheme of the ontogenesis control is proposed within the framework of which different types of parameters and dynamic variables are characterized. The concept of chaos is discussed with reference to ontogenesis.

Aging↗

[Radiation entropy and its role in the process of photosynthesis].

The paper deals with the following problems: 1) radiation entropy and the value of maximum performance coefficient of photosynthesizing systems eta m; 2) problem of physical meaning of eta m and on its association with real processes in photosynthesis. It has been shown that for calculating entropy of nonequilibrium radiation its origin should be known and that the value eta m does not practically limit the processes which proceed in photosynthesis.

Mathematics↗

[Physical model of initial stages of energy transformation during oxidative phosphorylation].

A model of non-dissipative energy transmission of activated electron into proton subsystem energy was considered. The model is based on the effect of resonance tunneling of the electrons, which provides for non-dissipative energy transmission. Within the scope of the model the energized proton formed in the protein membrane structure has enough energy to perform phosphorylation.

Energy Transfer↗

[Kinetics of primary photocycle stages of bacteriorhodopsin at low temperatures].

According to the changes of absorption spectra kinetics of two primary stages of bacteriorhodopsin photochemical cycle was studied in the temperature range 160 +/- 300 degrees K. It has been found that for K610-L550 transition in the range under study the rate-temperature relationship is described by Arrhenius law with the activation energy Ea = 0.68 eV. For L550-M412 transition Ea = 0.69 eV. The character of temperature relationship, of the rate and amplitude for this transition indicates that at T less than or equal to 270 degrees K a phase transition is possible.

Bacteriorhodopsins↗