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Biomedical subjects

D Rosenthal

Publications and source records attributed to D Rosenthal.

At least 217 records · Page 12Linked to original sources
PubMed1982

Nocturnal biofeedback for nocturnal bruxism.

Reports have appeared recently describing the successful reduction of nocturnal bruxism through nocturnal biofeedback. These claims of effective treatments rest mainly on the use of a single index of integrated masseter EMG levels as a measure of bruxism and are based only on short-term effects. The present study was conducted to provide a more rigorous evaluation of the effectiveness of nocturnal biofeedback for nocturnal bruxism through the use of all-night polysomnographic recordings. The results from multiple indices of bruxism are internally consistent and indicate that simple nocturnal biofeedback does not appear to be effective in reducing nocturnal bruxing. Recommendations are made for a more comprehensive approach to the treatment of nocturnal bruxism.

Adult↗
PubMed1982

Multiple cutaneous focal mucinoses with hypothyroidism.

A 54-year-old woman with myxedema had hundreds of discrete cutaneous mucinous papules, which responded dramatically to appropriate replacement therapy with L-thyroxine. Each lesion both clinically and histologically resembled a cutaneous focal mucinosis (cutaneous myxoma). Multiple cutaneous focal mucinoses are a previously undescribed manifestation of hypothyroidism that can be differentiated from other syndromes that have cutaneous mucinous deposits.

Female↗
PubMed1982

Albumin concentration in normal and pathological human thyroids.

1. The concentration of thyroid albumin was determined in 54 normal and pathological human thyroid tissue specimens obtained at surgery from 34 subjects who had received 125I prior to thyroidectomy. 2. The saline-soluble proteins were fractionated by gel filtration on Sephadex G-200 and the absorbance of the effluent containing albumin and hemoglobin was measured at 280 and 414 nm. The serum albumin content of the blood contaminating the tissue extract was calculated on the basis of hemoglobin determination (A414) and hematocrit values. This "intravascular albumin" was present in all extracts studied but accounted for less than 10% of the total thyroid albumin in normal tissue and even less in pathological specimens. "Extravascular albumin" was taken as the difference between total and "intravascular" albumin. 3. The amount of extravascular albumin in normal tissue (N = 20), 14.9 +/- 1.9 mg/g thyroid, was significantly lower than in adenomas (hot nodules, N = 7, 32.0 +/- 4.1; cold nodules, N = 16, 24.0 +/- 2.7), papillary carcinomas (N = 9, 51.1 +/- 16.7) and Hashimoto's thyroiditis (N = 2, 36.1 and 176.3). 4. In vivo labelling by 125I of the albumin fraction was demonstrated by Sephadex G-200 gel filtration and by cellulose acetate electrophoresis. Although the ratio of concentration of total albumin/thyroglobulin determined by electrophoresis was similar for 4 normal (0.263 +/- 0.046) and 5 pathological tissues (0.268 +/- 0.059), the relative distribution of radioactivity (total albumin/thyroglobulin) was significantly higher for pathological tissue (0.091 +/- 0.007) than for normal tissue (0.052 +/- 0.023), P less than 0.05. 5. The data suggest that most of the extravascular thyroid albumin is found within the follicle, and demonstrate that there is a significant increase in the concentration of extravascular thyroid albumin associated with several thyroid disorders.

Albumins↗
PubMed1981

Carotid endarterectomy. The unreliability of intraoperative monitoring in patients having had stroke or reversible ischemic neurologic deficit.

We reviewed 125 patients who had had stroke or reversible ischemic neurologic deficits (RIND) and who underwent carotid endarterectomy, with follow-up extending to six years. Phase I patients (n = 36) had endarterectomy and shunt placement at operation by surgeons' preference. The rate of postoperative neurologic deficit was 8%. Phase II patients (n = 36) had endarterectomy monitored by EEG and stump pressures. Postoperative deficits occurred in 9%. The EEGs and stump pressures in these patients were "normal"; therefore, no shunt was used. Phase III patients (n = 41) had endarterectomy again monitored by EEG and stump pressure. Despite normal EEGs or stump by EEG and stump pressure. Despite normal EEGs or stump pressure, all patients underwent endarterectomy with a temporary indwelling shunt. No complications occurred. In 368 patients operated on for transient ischemic attacks alone, the operative stroke rate was 1.6%. Stump pressure and EEG are unreliable indicators of cerebral perfusion during carotid endarterectomy in patients who have suffered stroke or RIND. Use of a temporary shunt is indicated in all of these patients.

Adult↗
PubMed1981

Surgical correction of the kinked carotid artery.

The hemodynamic significance of the kinked internal carotid artery and cerebrovascular insufficiency are demonstrated. Several procedures have been devised to correct a carotid kink, but these involve resection or excision of the internal, external or common carotid artery. We currently prefer a reimplantation technique whereby preservation of the external carotid is maintained, resection of the internal carotid artery is avoided and, when necessary, endarterectomy may be safely employed.

Brain Ischemia↗
PubMed1981

Changing trends in causalgia.

The term causalgia as currently understood encompasses a wider range of post-traumatic disabilities than Mitchell's original definition as burning pain. In this series, orthopedic injury replaced penetrating trauma as the most common initiating event. Injury to a peripheral nerve may be ill-defined or absent. Serious disability may arise from what appears to be a minor injury. When causalgia is recognized and appropriate therapy instituted, nearly all patients improve.

Causalgia↗
PubMed1981

Review of colorectal cancer in patients under age 40 years.

Brooke Army Medical Center Tumor Registry records from 1947 through 1980 were reviewed. One hundred forty of 819 patients with colorectal cancer were aged 40 or less. The 5 year survival rate was 35 percent and the 10 year survival rate 32 percent. The predominant presenting symptoms were bleeding, pain and change of bowel habits. The median duration of symptoms was 3 months. There were no Dukes'A patients. The 5 and 10 year survival rates in 19 Dukes' B patients were 67 percent. Thirty-three Dukes' C patients had 5 and 10 year survival rates of 37 and 30 percent, respectively. In 42 Dukes' D patients, however, there were no 5 year survivors, and the mean length of survival was only 10 months. Our findings support previous surveys which have concluded that stage at the time of diagnosis, rather than symptoms, duration or patient age, is the most accurate prognostic factor.

Adenocarcinoma↗
PubMed1981

Hemodynamic assessment and surgical correction of the kinked internal carotid artery.

A fluid-filled oculoplethysmography (OPG) was used to assess carotid artery flow in 50 patients with symptoms of cerebral ischemia. Based on positioned OPG and angiographic studies, 20 patients had angioplastic procedures. At operation, positional electromagnetic flow measurements were obtained to confirm the preoperative noninvasive findings. Electromagnetic flow reductions were identified in 18 patients with positive preoperative positional OPGs. A high correlation between noninvasive testing data and intraoperative flow measurements suggests that positional OPG testing is helpful in identifying hemodynamically significant kinking of the internal carotid artery.

Angiography↗
PubMed1981

Familial variant of dermatofibroma with malignancy in the proband.

Multiple fibrous histiocytomas of the dermis (dermatofibromas) were found in six males of one family. A number of the tumors fell within the histologic patterns commonly encountered in dermatofibromas, but some were unusually large and others were cytologically atypical. In addition, the proband died of a malignant fibrous histiocytoma of the lung. We believe that this is a syndrome and a familial variant of a common dermal entity.

Fibroma↗
PubMed1980

Method for analysis of polybrominated biphenyls by gas chromatography mass spectrometry.

Gas chromatography using a short packed column (45 cm, 0.2 cm i.d., 2% OV-101 on Gas-Chrom Q) with mass spectrometric detection in the selected ion monitoring mode has been found satisfactory for the analysis of lower as well as higher polybrominated biphenyls. Acceptable sensitivity (< 1 ng) may be achieved for this method by focusing selectively at either the low (m/z 20-600) or the high m/z 600-1000) range of the quadrupole filter (low range for mono- through hexabromobiphenyl, high range for hexa- through decabromobiphenyl). A tuning technique has been developed for low range and high range polybrominated biphenyls using the ion abundances of perfluorotributylamine as a standard. Standard ions for the quantitation of mono- through decabromo-biphenyls were selected and validated. The technique was applied to the analysis of a variety of environmental samples.

Animals↗
PubMed1980

A primate model for the study of the interaction of 111In-labeled baboon platelets with Dacron arterial prostheses.

This paper presents early experience with a primate model for the noninvasive study of the interaction of circulating platelets with healing arterial prostheses. These experiments demonstrate that baboon platelets can be isolated and labeled with 111Indium with high efficiency using a sterile technique. Platelets subjected to this process have a linear life span similar to that of 51Chromium-labeled baboon platelets. The high energy gamma emission of 111Indium oxine allows for external scanning using a standard gamma camera. The small quantity of 111Indium-labeled platelets in the region of the graft can be discriminated from the surrounding blood vessel and quantitated by gamma camera imaging and computer analysis. There was a significant increase in the platelet deposition on prosthetic surfaces observed 5--48 hours after graft implantation and injection of 111Indium-labeled autologous platelets.

Animals↗
PubMed1980

Diagnosing deep vein thrombosis by Doppler ultrasound and impedance plethysmography.

To evaluate the diagnostic accuracy of Doppler ultrasound (DU) and impedance plethysmography (IPG) in deep vein thrombosis (DVT), hospital records of 904 patients having 1,084 studies of blood flow in the lower extremities were retrospectively reviewed, and 544 were found abnormal. In 128, both DU and IPG showed abnormalities, 86 had only DU evidence of abnormalities, and 330 had only IPG abnormalities. Fifty-one patients with abnormal results of both DU and IPG studies had ascending phlebography, which in 47 documented the presence of DVT, for a diagnostic accuracy of 92%. On the basis of DU/IPG testing, or extenuating clinical circumstances, 135 patients considered at high risk for pulmonary emboli had ventilation-perfusion lung scans. Of these, 44 had roentgenographic evidence of pulmonary emboli. While ascending phlebography remains the definitive study for documenting the presence of DVT, DU/IPG testing has a high accuracy rate, is noninvasive, readily reproducible, inexpensive, and simple to perform. When results of DU/IPG studies are abnormal a baseline ventilation lung scan should be done which, if questionable, should be followed by pulmonary arteriography.

Humans↗
PubMed1980

Finger arthrography.

The use of arthrography in patients with chronic finger complaints is discussed. Magnification arthrography was performed to assist the clinical evaluation of 15 patients with pain in the metacarpal-phalangeal or proximal interphalangeal joints. Conditions detected include collateral ligament laxity, extravasation around the volar plate, and fibrous ankylosis. Demonstration of normal articular cartilage was important for clinical management in some patients. Direct radiographic magnification was considered useful for best visualization, but tomography was not helpful.

Adolescent↗